2 Results for "

HS25

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "HS25" in MCE Product Catalog:

Cat. No.: HY-107176A
CAS No.: 1266548-74-6
Synonyms: HS-25
Target:  

Others

Research Areas:  

Metabolic Disease

Hyzetimibe is a cholesterol absorption inhibitor. Hyzetimibe blocks the intestinal absorption of cholesterol and phytol. Hyzetimibe is well tolerated in animal models, with an LDmax 2000 mg/kg in rats and an LDmax 500 mg/kg in rhesus monkeys .
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Cat. No.: HY-107176
CAS No.: 1266548-75-7
Synonyms: (E)-HS-25
Research Areas:  

Infection Metabolic Disease

(E)-Hyzetimibe ((E)-HS-25) (Compound I-1Z) is the trans isomer of Hyzetimibe (HY-107176A), a cholesterol-lowering agent. (E)-Hyzetimibe has cholesterol acyltransferase (ACTA) inhibitory activity, but its cholesterol-lowering effect is relatively weak. (E)-Hyzetimibe can inhibit the entry of hepatitis C virus (HCV) into host cells, and it has a synergistic effect when used in combination with interferon-α. (E)-Hyzetimibe can be used for the study of HCV infection .
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