1266548-74-6
Chemical Structure
Hyzetimibe
Synonym(s): HS-25
- CAS No.: 1266548-74-6
- Formula:C25H21F2NO3
- Molecular Weight:421.44
IUPAC Name: (3R,4S)-1-(4-fluorophenyl)-3-((Z)-3-(4-fluorophenyl)-4-hydroxybut-2-en-1-yl)-4-(4-hydroxyphenyl)azetidin-2-one
InChIKey: HEHHPZYUXSFAPV-SMOXZEHUSA-N
SMILES: OC/C(C1=CC=C(C=C1)F)=C\C[C@@H]2[C@](C3=CC=C(C=C3)O)([H])N(C4=CC=C(C=C4)F)C2=O
Biological Activity: Hyzetimibe is a cholesterol absorption inhibitor. Hyzetimibe blocks the intestinal absorption of cholesterol and phytol. Hyzetimibe is well tolerated in animal models, with an LDmax 2000 mg/kg in rats and an LDmax 500 mg/kg in rhesus monkeys[1].
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Hyzetimibe | Hyzetimibe is a cholesterol absorption inhibitor. Hyzetimibe blocks the intestinal absorption of cholesterol and phytol. Hyzetimibe is well tolerated in animal models, with an LDmax 2000 mg/kg in rats and an LDmax 500 mg/kg in rhesus monkeys. | |||||||||||||||||||||
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Keywords
