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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
13 Results for "
HSPA1A
" in MedChemExpress (MCE) Product Catalog:
Products (13)
13 Results for "HSPA1A" in MCE Product Catalog:
1
Cat. No.: HY-162567
CAS No.: 2716909-84-9
AP-4-139B is a blood-brain barrier-permeable HSP70 inhibitor with a IC50 of 180 nM against hHSP70. AP-4-139B binds directly to HSP70 and inhibits its ATPase activity. AP-4-139B promotes Autophagy by increasing the phosphorylation of Beclin-1. AP-4-139B exerts antitumor effects in preclinical models of colorectal cancer and pancreatic ductal adenocarcinoma [1] .
Cat. No.: HY-RS06424
Target:
Research Areas:
HSPA1A Human Pre-designed siRNA Set A contains three designed siRNAs for HSPA1A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS18094
Target:
Research Areas:
Hspa1a Mouse Pre-designed siRNA Set A contains three designed siRNAs for Hspa1a gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS24569
Target:
Research Areas:
Hspa1a Rat Pre-designed siRNA Set A contains three designed siRNAs for Hspa1a gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P701004
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: HSP70-1; HSPA1A; HSP72 ; HSPA1; HSX70
Cat. No.: HY-P85508
Synonyms: DAQB 147D11.1 001; FLJ54303; FLJ54370; FLJ54392; FLJ54408; FLJ75127; Heat shock 70 kDa protein 1; Heat shock 70 kDa protein 1/2; Heat shock 70 kDa protein 1A/1B; heat shock 70kDa protein 1A; Heat shock 70kDa protein 1B; Heat shock induced protein; heat shock protein 70; HSP70 1; HSP70 2; HSP70-1/HSP70-2; HSP70-1A; HSP70.1; HSP70.1/HSP70.2; HSP70I; HSP71_HUMAN; HSP72; HSPA1; HSPA1A; HSPA1B; XXbac BCX40G17.3 001.
Cat. No.: HY-P73105
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: Heat shock 70 kDa protein 1B; HSP70-2; HSPA1B; HSP72
Species:
Source:
Cat. No.: HY-117252
CAS No.: 1118861-60-1
HS-72 is a selective allosteric inducible heat shock protein 70 Hsp70i inhibitor. HS-72 reduces ATP affinity of Hsp70i, elevates caspase 3/7 apoptotic activity, and promotes degradation of Hsp70 client proteins, including HER2 and Akt, and blocks DENV entry by disrupting Hsp70i association with the DENV receptor complex. HS-72 can be used for breast cancer and dengue virus infection research [1] .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
