8 Results for "

Human β-CGRP

" in MedChemExpress (MCE) Product Catalog:
Products (8)

8 Results for "Human β-CGRP" in MCE Product Catalog:

12
12 Publications Verification
Cat. No.: HY-15498
CAS No.: 1289023-67-1
Purity:  99.94%
Synonyms: BMS-927711; BHV-3000
Target:  

CGRP Receptor

Research Areas:  

Neurological Disease

Rimegepant (BMS-927711; BHV-3000) is an orally bioavailable and blood-brain barrier permeable antagonist of CGRP and AMY1 receptors, with a pIC50 of 8.01 and a Ki of 0.027 nM for human CGRP receptors. Rimegepant antagonizes cAMP production induced by αCGRP, βCGRP and amylin at CGRP and AMY1 receptors in humans, rats and mice, as well as at rat AMY3 receptors. Rimegepant can be used in research related to migraine .
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1
1 Cited Publications
Cat. No.: HY-P1548
CAS No.: 101462-82-2
Synonyms: Human β-CGRP; CGRP-II (Human)
β-CGRP, human (Human β-CGRP) is one of calcitonin peptides, acts via the complex of calcitonin-receptor-like receptor (CRLR) and receptor-activity-modifying protein (RAMP), with IC50s of 1 nM and 300 nM for CRLR/RAMP1 and CRLR/RAMP2 in cells .
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1
1 Cited Publications
Cat. No.: HY-P1548A
Synonyms: Human β-CGRP TFA; CGRP-II (Human) TFA
β-CGRP, human TFA (Human β-CGRP TFA) is one of calcitonin peptides, acts via the complex of calcitonin-receptor-like receptor (CRLR) and receptor-activity-modifying protein (RAMP), with IC50s of 1 nM and 300 nM for CRLR/RAMP1 and CRLR/RAMP2 in cells .
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Cat. No.: HY-P99017
CAS No.: 1644539-04-7
Synonyms: ALD-403

Target:  

CGRP Receptor

Research Areas:  

Neurological Disease

Eptinezumab (ALD-403) is a human monoclonal antibody targeting the α and β subtypes of human calcitonin gene-related peptide (CGRP). Eptinezumab binds to the CGRP ligand and blocks its binding to endogenous CGRP receptors, thereby inhibiting receptor activation. Eptinezumab can be used in research related to migraine .
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Cat. No.: HY-P1548B
Synonyms: Human β-CGRP acetate; CGRP-II (Human) acetate
β-CGRP, human acetate (Human β-CGRP acetate) is one of calcitonin peptides, acts via the complex of calcitonin-receptor-like receptor (CRLR) and receptor-activity-modifying protein (RAMP), with IC50s of 1 nM and 300 nM for CRLR/RAMP1 and CRLR/RAMP2 in cells .
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Cat. No.: HY-15498S
Synonyms: BMS-927711-d4; BHV-3000-d4
Rimegepant-d4 (BMS-927711-d4) is the deuterium labeled Rimegepant (HY-15498). Rimegepant (BMS-927711) is an orally bioavailable and blood-brain barrier permeable antagonist of CGRP and AMY1 receptors, with a pIC50 of 8.01 and a Ki of 0.027 nM for human CGRP receptors. Rimegepant antagonizes cAMP production induced by αCGRP, βCGRP and amylin at CGRP and AMY1 receptors in humans, rats and mice, as well as at rat AMY3 receptors. Rimegepant can be used in research related to migraine .
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Cat. No.: HY-P7706
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CALCB; Beta-Type CGRP; Prev. CALC2; Beta-CGRP; CGRP-II; FLJ30166; Calcitonin Gene-Related Peptide II; CGRP2; Calcitonin Gene-Related Peptide 2; Calcitonin Related Polypeptide Beta; Calcitonin 2
Species:  
Source:  
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Cat. No.: HY-P75600
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CALCB; Beta-Type CGRP; Prev. CALC2; Beta-CGRP; CGRP-II; FLJ30166; Calcitonin Gene-Related Peptide II; CGRP2; Calcitonin Gene-Related Peptide 2; Calcitonin Related Polypeptide Beta; Calcitonin 2
Species:  
Source:  
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