1 Result for "

Hydroxyhydroquinone (Standard)

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "Hydroxyhydroquinone (Standard)" in MCE Product Catalog:

1,2,4-Trihydroxybenzene (Standard)
1,2,4-Trihydroxybenzene (Standard)
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Cat. No.: HY-W010451R
CAS No.: 533-73-3
Synonyms: Hydroxyhydroquinone (Standard)
Category:  

Microorganisms Phenols Polyphenols

Target:  

Reference Standards PERK Potassium Channel Apoptosis Eukaryotic Initiation Factor (eIF)

1,2,4-Trihydroxybenzene (Hydroxyhydroquinone) (Standard) is the analytical standard of 1,2,4-Trihydroxybenzene (HY-W010451). This product is intended for research and analytical applications. 1,2,4-Trihydroxybenzene (Hydroxyhydroquinone) is an ER stress inducer that targets proteins such as PKR-like ER kinase PERK to induce cytotoxicity. 1,2,4-Trihydroxybenzene selectively activates eIF2α phosphorylation, activates the PERK-eIF2α signaling pathway and induces stress granule formation. 1,2,4-Trihydroxybenzene subsequently exacerbates oxidative stress and causes DNA double-strand breaks, destroying organelles such as mitochondria and ER, and inducing cell death. 1,2,4-Trihydroxybenzene also has the potential to exhibit anti-tumor effect, increase blood pressure, and relieve spasm .
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