11 Results for "

IL-2Rα

" in MedChemExpress (MCE) Product Catalog:
Products (11)

11 Results for "IL-2Rα" in MCE Product Catalog:

Cat. No.: HY-P990281

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Anti-Mouse CD25/IL-2Rα Antibody (PC-61.5.3) is a rat-derived IgG1 λ type antibody inhibitor, targeting to mouse CD25/IL-2Rα. Anti-Mouse CD25/IL-2Rα Antibody (PC-61.5.3) can deplete CD25+ T cells. Anti-Mouse CD25/IL-2Rα Antibody (PC-61.5.3) can be used for the researches of immunology and inflammation, such as atopic dermatitis [2].
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Cat. No.: HY-P991740

Research Areas:  

Cancer

IBI-363 is a PD-1/IL-2 bispecific antibody with functions of blocking the PD-1/PD-L1 pathway and activating the IL-2 pathway. The IL-2 arm of IBI-363 retains affinity for IL-2Rα but attenuates binding ability to IL-2Rβ and IL-2Rγ to reduce toxicity. The PD-1 binding arm of IBI-363 enables PD-1 blockade and selective delivery of IL-2. IBI-363 can be used in cancer research, such as non-small cell lung cancer .
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Cat. No.: HY-119424
CAS No.: 515846-21-6
Purity:  98.11%
Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

SP4206 is an IL-2/IL-2Rα interaction inhibitor. SP4206 binds with high affinity (Kd=70 nM) to IL-2 and blocks binding to its natural receptor IL-2Rα (Kd=10 nM) .
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Cat. No.: HY-P1453A
Research Areas:  

Cancer

CMD178 TFA is a lead peptide that consistently reduced the expression of Foxp3 and STAT5 induced by IL-2/s IL-2Rα signaling and inhibits Treg cell development .
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Cat. No.: HY-121743
CAS No.: 193744-04-6
Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Ro26-4550 is a low micromolar antagonist of IL-2/IL-2Rα binding with an IC50 value of 3 μM .
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Cat. No.: HY-P990866

Target:  

Interleukin Related

Research Areas:  

Cancer

Anti-CD25/IL-2Rα Antibody (7G7B6) is an anti-human CD25/IL-2Rα IgG2a monoclonal antibody. Anti-CD25/IL-2Rα Antibody (7G7B6) can inhibit the growth of tumors. Anti-CD25/IL-2Rα Antibody (7G7B6) can be used for research on leukemia. The recommend isotype control of Anti-CD25/IL-2Rα Antibody (7G7B6): Mouse IgG2a kappa, Isotype Control (HY-P99978) .
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Cat. No.: HY-103390
CAS No.: 1217448-66-2
Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Ro26-4550 TFA is a low micromolar antagonist of IL-2/IL-2Rα binding with an IC50 value of 3 μM .
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Cat. No.: HY-P1453
Research Areas:  

Cancer

CMD178 is a lead peptide that consistently reduced the expression of Foxp3 and STAT5 induced by IL-2/s IL-2Rα signaling and inhibits Treg cell development .
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Cat. No.: HY-P99664
CAS No.: 152981-31-2

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Inolimomab is an anti-interleukin-2 receptor (IL-2R) α chain monoclonal antibody. Inolimomab improves the survival rate in the early research of treating acute graft-versus-host disease (aGVHD) [2].
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Cat. No.: HY-P991749

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Anti-Rat CD25 Antibody (OX-39) recognizes the 55 kDa low-affinity interleukin-2 receptor α chain (IL-2R α, CD25). Anti-Rat CD25 Antibody (OX-39) interacts with a single class of sites on the alpha chain of the rat R-IL2 with a high affinity (Kd of 0.8 nM) and competes with IL2 binding on this chain (Ki of 0.53 nM). Anti-Rat CD25 Antibody (OX-39) is a weak inhibitor in vitro on IL2-induced proliferation and in vivo on allograft rejection. Recommend Isotype Controls: Mouse IgG1 kappa, Isotype Control (HY-P99977) .
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Cat. No.: HY-P992161
REGN-10597, composed of an anti-huPD-1-targeting antibody and IL2Ra-IL2 moiety, is a PD-1-dependent IL-2 agonist. REGN-10597 binds PD-1 to deliver masked native IL-2 to PD-1+ T cells, engaging trimeric IL-2 receptors to activate downstream signaling. REGN-10597 can be used for the research on melanoma, prostate cancer, colorectal cancer, and ovarian cancer [2] .
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