6 Results for "

Inactive Analogue

" in MedChemExpress (MCE) Product Catalog:
Products (6)

6 Results for "Inactive Analogue" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-136658
CAS No.: 1313019-65-6
Purity:  98.02%
Target:  

STAT Apoptosis

Research Areas:  

Cancer

STAT3-IN-48 is a Sorafenib analogue and potently inhibits the phosphorylation of STAT3. STAT3-IN-48 induces cell apoptosis through SHP-1 dependent STAT3 inactivation. STAT3-IN-48 does not inhibit kinase activity and has anticancer effects .
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Cat. No.: HY-P1928
CAS No.: 330936-69-1
Target:  

Bcl-2 Family

Research Areas:  

Neurological Disease Endocrinology

Humanin, an anti-apoptotic peptide of 24 amino acids, is a Bax inhibitor. Humanin prevents the translocation of Bax from cytosol to mitochondria, blocks Bax from the inactive to active conformation. Humanin is a mitochondria-associated peptide with a neuroprotective effect against AD-related neurotoxicity. Humanin also improves overall insulin sensitivity in animal. Humanin are related to aging .
Humanin analogue, in which the serine at position 14 is replaced by glycine, names HNG .
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Cat. No.: HY-124479A
CAS No.: 6901-14-0
Purity:  99.70%
Target:  

Drug Derivative

Research Areas:  

Cancer

γ-Lumicolchicine is an inactive analogue of Colchicine (HY-16569) that can be used as an experimental control for Colchicine action .
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Cat. No.: HY-P3072
CAS No.: 145854-61-1
Target:  

mTOR

Research Areas:  

Metabolic Disease

Mastoparan 17 is a tetradecapeptide. Mastoparan 17 is an inactive analogue of Mastoparan (HY-P0246) .
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Cat. No.: HY-W140208
CAS No.: 2404-87-7
Target:  

Cytochrome P450

Research Areas:  

Neurological Disease

3-Phenylthiophene (Compound 25) is a CYP2A6 inhibitor with a Ki value of 3.3 μM. The Ki values for CYP2E1, CYP2B6, CYP2C9, and CYP2C19 are 9.7, 14, 112, and 107 μM respectively. It shows no significant inhibition on CYP3A4 and CYP2D6. 3-Phenylthiophene can be used in smoking cessation research .
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Cat. No.: HY-111176
CAS No.: 90536-15-5
Synonyms: 3-Phenyl-2-sulfanylpropanoic acid
Target:  

Cathepsin

Research Areas:  

Others

PD 145305 (3-Phenyl-2-sulfanylpropanoic acid) is an inactive analogue of PD150606. PD150606 is a selective calpain inhibitor .
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