1313019-65-6

STAT3-IN-48 Chemical Structure
1313019-65-6

Chemical Structure

STAT3-IN-48

  • CAS No.: 1313019-65-6
  • Formula:C21H13ClF3N3O2
  • Molecular Weight:431.80

IUPAC Name: 1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea

InChIKey: HVPZDXDXIQZKHU-UHFFFAOYSA-N

SMILES: O=C(NC1=CC=C(OC2=CC=C(C#N)C=C2)C=C1)NC3=CC=C(Cl)C(C(F)(F)F)=C3

Biological Activity: STAT3-IN-48 is a Sorafenib analogue and potently inhibits the phosphorylation of STAT3. STAT3-IN-48 induces cell apoptosis through SHP-1 dependent STAT3 inactivation. STAT3-IN-48 does not inhibit kinase activity and has anticancer effects[1].

Cat. No. Product Name Purity Description Pricing
HY-136658 		STAT3-IN-48 98.64% STAT3-IN-48 is a Sorafenib analogue and potently inhibits the phosphorylation of STAT3. STAT3-IN-48 induces cell apoptosis through SHP-1 dependent STAT3 inactivation. STAT3-IN-48 does not inhibit kinase activity and has anticancer effects.
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