4 Results for "

JFH1

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "JFH1" in MCE Product Catalog:

12
12 Publications Verification
Cat. No.: HY-N6798
CAS No.: 35891-70-4
Synonyms: Thermozymocidin; ISP-I
Myriocin (Thermozymocidin), a fungal metabolite could be isolated from Myriococcum albomyces, Isaria sinclairi and Mycelia sterilia, is a potent inhibitor of serine-palmitoyl-transferase (SPT) and a key enzyme in de novo synthesis of sphingolipids. Myriocin suppresses replication of both the subgenomic HCV-1b replicon and the JFH-1 strain of genotype 2a infectious HCV, with an IC50 of 3.5 μg/mL for inhibiting HCV infection [1] .
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8
8 Cited Publications
Cat. No.: HY-15745A
CAS No.: 1621884-22-7
Purity:  99.31%
Target:  

HCV

Research Areas:  

Infection

PSI-7409 tetrasodium is an active 5'-triphosphate metabolite of sofosbuvir (PSI-7977), inhibiting HCV NS5B polymerases, with IC50s of 1.6, 2.8, 0.7 and 2.6 μM for GT 1b_Con1, GT 2a_JFH1, GT 3a, and GT 4a NS5B polymerases, respectively.
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3
3 Cited Publications
Cat. No.: HY-148647
CAS No.: 1000120-98-8
Synonyms: ISIS 301012 free base
Target:  

Apolipoprotein HCV

Research Areas:  

Infection

Mipomersen (ISIS 301012 free base) is an antisense oligonucleotide inhibitor of apolipoprotein B (apoB). Mipomersen has anti-HCV effect and reduces the infectivity of the HCV. Mipomersen can be used for the research of homozygous familial hypercholesterolemia (HoFH) [1] .
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Cat. No.: HY-N6798R
CAS No.: 35891-70-4
Synonyms: Thermozymocidin (Standard); ISP-I (Standard)
Myriocin (Standard) is the analytical standard of Myriocin. This product is intended for research and analytical applications. Myriocin (Thermozymocidin), a fungal metabolite could be isolated from Myriococcum albomyces, Isaria sinclairi and Mycelia sterilia, is a potent inhibitor of serine-palmitoyl-transferase (SPT) and a key enzyme in de novo synthesis of sphingolipids. Myriocin suppresses replication of both the subgenomic HCV-1b replicon and the JFH-1 strain of genotype 2a infectious HCV, with an IC50 of 3.5 μg/mL for inhibiting HCV infection[1][2][3].
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