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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
6 Results for "
KLHL20
" in MedChemExpress (MCE) Product Catalog:
Products (6)
6 Results for "KLHL20" in MCE Product Catalog:
Referencia número: HY-172563A
Target:
Áreas de investigación:
BTR2000 TFA, a specifically KLHL20 ligand, is capable of binding to the KLHL20 Kelch domain with high affinity. BTR2000 TFA can be used as a ligand for E3 ligase for the synthesis of BTR2004 (HY-172562) .
Referencia número: HY-172564
Áreas de investigación:
BTR2000-Gly-Gly-Gly is a E3 ligase ligand-linker conjugate (KLHL20) that can be used for the synthesis of PROTAC BTR2004 (HY-172562) .
Referencia número: HY-RS07362
Target:
Áreas de investigación:
KLHL20 Human Pre-designed siRNA Set A contains three designed siRNAs for KLHL20 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Referencia número: HY-172563
Target:
Áreas de investigación:
BTR2000, a specifically KLHL20 ligand, is capable of binding to the KLHL20 Kelch domain with high affinity. BTR2000 can be used as a ligand for E3 ligase for the synthesis of BTR2004 (HY-172562) .
Referencia número: HY-172564A
Áreas de investigación:
BTR2000-Gly-Gly-Gly TFA is a E3 ligase ligand-linker conjugate (KLHL20) that can be used for the synthesis of PROTAC BTR2004 (HY-172562) .
Referencia número: HY-172562
No. CAS: 3093583-69-5
Target:
Áreas de investigación:
BTR2004 is a selective BET family (BRD2/3/4) protein PROTAC degrader. BTR2004 forms a ternary complex with BRD proteins and KLHL20, inducing ubiquitination and proteasomal degradation through the UPS pathway. BTR2004 is promising for research of PC3 prostate cancer and MDA-MB-231 breast cancer cell lines .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
