4 Results for "

KPT185

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "KPT185" in MCE Product Catalog:

Cat. No.: HY-15611
CAS No.: 1333151-73-7
Purity:  98.21%
Target:  

CRM1

Research Areas:  

Cancer

KPT-185 is an orally bioavailable and selective inhibitor of CRM1 and displays potent antiproliferative properties at submicromolar concentrations (IC50=100-500 nM), induces apoptosis, cell-cycle arrest, and myeloid differentiation in AML cell lines and patient blasts .
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13
13 Cited Publications
Cat. No.: HY-17536
CAS No.: 1393477-72-9
Synonyms: KPT-330
Target:  

CRM1 PANoptosis

Research Areas:  

Infection Cancer

Selinexor (KPT-330) is an analog of KPT-185 (HY-15611). Selinexor is an orally active, selective CRM1 inhibitor that inhibits tumor growth by inducing PANoptosis .
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Cat. No.: HY-17536S
Synonyms: KPT-330-d5
Selinexor-d5 (KPT-330-d5) isthe deuterium labeled Selinexor (HY-17536). Selinexor (KPT-330), an analog of KPT-185, is an orally active and selective CRM1 inhibitor .
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Cat. No.: HY-17536R
CAS No.: 1393477-72-9
Synonyms: KPT-330 (Standard)
Research Areas:  

Cancer

Selinexor (Standard) is the analytical standard of Selinexor. This product is intended for research and analytical applications. Selinexor (KPT-330) is an analog of KPT-185 (HY-15611). Selinexor is an orally active, selective CRM1 inhibitor that inhibits tumor growth by inducing PANoptosis .
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