2 Results for "

L652343

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "L652343" in MCE Product Catalog:

Cat. No.: HY-105933
CAS No.: 107008-29-7
L-652343 is a dual cyclooxygenase/lipoxygenase inhibitor. L-652343 can inhibit the production of LTB4 in isolated human polymorphonuclear leukocytes treated with Calcimycin (HY-N6687) (IC50: 1.4 μM), but it is inactive in whole blood. L-652343 can be used in the research of inflammatory and immune diseases .
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Cat. No.: HY-113691
CAS No.: 102565-09-3
Target:  

Lipoxygenase

Research Areas:  

Others

(E)-L-652343 is a compound with potent cyclooxygenase and 5-lipoxygenase inhibitory activity. (E)-L-652343 can effectively inhibit the synthesis of products of these two pathways in vivo. (E)-L-652343 showed high sensitivity and specificity in the detection of geometric isomers in canine and human plasma. (E)-L-652343 showed selective metabolism in vivo, and the elimination rate of the E isomer was faster than that of the Z isomer .
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