107008-29-7
Chemical Structure
L-652343
- CAS. Nr.: 107008-29-7
- Formula:C22H14F3NO2S2
- Molecular Weight:445.48
IUPAC Name: (E)-3-hydroxy-N-(2-phenyl-2-(thiophen-2-yl)vinyl)-5-(trifluoromethyl)benzo[b]thiophene-2-carboxamide
InChIKey: MWRHQMNEBAXDOF-FOWTUZBSSA-N
SMILES: OC1=C(C(N/C=C(C2=CC=CC=C2)/C3=CC=CS3)=O)SC4=C1C=C(C(F)(F)F)C=C4
Biological Activity: L-652343 is a dual cyclooxygenase/lipoxygenase inhibitor. L-652343 can inhibit the production of LTB4 in isolated human polymorphonuclear leukocytes treated with Calcimycin (HY-N6687) (IC50: 1.4 μM), but it is inactive in whole blood. L-652343 can be used in the research of inflammatory and immune diseases[1].
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L-652343 | L-652343 is a dual cyclooxygenase/lipoxygenase inhibitor. L-652343 can inhibit the production of LTB4 in isolated human polymorphonuclear leukocytes treated with Calcimycin (HY-N6687) (IC50: 1.4 μM), but it is inactive in whole blood. L-652343 can be used in the research of inflammatory and immune diseases. | |||||||||||||||||||||
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Keywords
