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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
9 Results for "
LID
" in MedChemExpress (MCE) Product Catalog:
Products (9)
9 Results for "LID" in MCE Product Catalog:
3
Target:
Research Areas:
Apraclonidine hydrochloride (ALO 2145), a selective α2 and weak α1 receptor agonist activity, effectively lowers intraocular pressure (IOP) in human eyes. Apraclonidine hydrochloride is a topical ophthalmic solution and has the ability to elevate the eye lid .
2
2 Cited Publications
Cat. No.: HY-P1335
CAS No.: 103429-32-9
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Research Areas:
2
2 Cited Publications
Cat. No.: HY-P1335A
Target:
Research Areas:
Synonyms: ADX48621
Target:
Research Areas:
Dipraglurant (ADX48621) is a potent, selective, orally active and brain penetrant mGluR5 negative allosteric modulator (NAM), with an IC50 of 21 nM. Dipraglurant can reduce Levodopa-induced dyskinesia (LID) in vivo . Dipraglurant is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Cat. No.: HY-N7862
CAS No.: 11094-59-0
Target:
Cat. No.: HY-12720AR
CAS No.: 73218-79-8
Synonyms: ALO 2145 (Standard)
Research Areas:
Apraclonidine (hydrochloride) (Standard) is the analytical standard of Apraclonidine (hydrochloride). This product is intended for research and analytical applications. Apraclonidine hydrochloride (ALO 2145), a selective α2 and weak α1 receptor agonist activity, effectively lowers intraocular pressure (IOP) in human eyes. Apraclonidine hydrochloride is a topical ophthalmic solution and has the ability to elevate the eye lid .
Cat. No.: HY-E0225
compounds
0.5 mL 96-Well Tube Rack, compliant with the industry-standard SBS (Society for Biomolecular Screening) specifications. This product features a sliding lock mechanism on the lid to prevent tube dislodgement. The side of the rack is equipped with an identifiable barcode for easy compound storage and retrieval. The matching tube (HY-E0224) is made from the same material as this tube, effectively preventing uneven expansion issues during freeze-thaw cycles.
Cat. No.: HY-L022M
3,238 compounds
New drug development is a time-consuming and high-cost process. Drug repurposing (also called drug repositioning, reprofiling or re‑tasking) offers various advantages over developing an entirely new drug for a given indication. First, the risk of failure is lower. Second, the time frame for drug development can be reduced. Third, less investment is needed. Approved drugs have identified bioactivities, good pharmacokinetic characteristics and safety which are suitable for drug repurposing.
MCE owns a unique collection of 3,238 approved compounds which have been completed extensive preclinical and clinical studies and have well-characterized bioactivities, safety and bioavailability properties. The package of this library is 96-well microplate with peelable foil seal, which makes the screening process easier and faster.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
