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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
16 Results for "
LNP1
" in MedChemExpress (MCE) Product Catalog:
Products (16)
16 Results for "LNP1" in MCE Product Catalog:
Art. -Nr.: HY-W598178
CAS. Nr.: 2227214-78-8
93-O17O is a chalcogen-containing ionizable cationic lipidoid that used in the formation of lipid nanoparticles (LNPs) .
Art. -Nr.: HY-W590531
CAS. Nr.: 1624618-02-5
Target:
Forschungsgebiete:
80-O16B is an ionizable cationic lipid containing disulfide bonds that can be used to prepare lipid nanoparticles (LNP) .
Art. -Nr.: HY-RS07729
Target:
Forschungsgebiete:
LNP1 Human Pre-designed siRNA Set A contains three designed siRNAs for LNP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Art. -Nr.: HY-160578
CAS. Nr.: 1257309-90-2
Synonyms: N-Cholesteryl succinyl glucosamine
Glucosamine Cholesterol (N-Cholesteryl succinyl glucosamine) is a glucosamine-based lipid conjugate, and can be used in the formation of lipid nanoparticles (LNPs) .
Art. -Nr.: HY-153375
CAS. Nr.: 2430034-00-5
Art. -Nr.: HY-153376
CAS. Nr.: 2226547-32-4
Art. -Nr.: HY-171951
31hP is an asymmetric A 3 lipid. 31hP can facilitate in vivo luciferase expression. 31hP can be rapidly degraded in the presence of esterase owing to two biocleavable ester bonds. 31hP can be used in the synthesis of lipid nanoparticles (LNPs) .
Art. -Nr.: HY-159869
CAS. Nr.: 2935435-86-0
G0-C14 analog is a G0-C14 derivative. G0-C14 is an ionizable cationic lipid that can be used to synthesize lipid nanoparticles (LNP) .
Art. -Nr.: HY-174286
CAS. Nr.: 119904-40-4
C16-18:1 PE is a lipid. C16-18:1 PE has the activity of promoting membrane fusion and enhancing endosomal escape, which can significantly improve the delivery efficiency of mRNA. C16-18:1 PE is used in the synthesis of lipid nanoparticles (LNP) .
Art. -Nr.: HY-RS07731
Target:
Forschungsgebiete:
LNPK Human Pre-designed siRNA Set A contains three designed siRNAs for LNPK gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Art. -Nr.: HY-160580
CAS. Nr.: 2933216-12-5
G1-OC2-K3-E10 is an ionizable lipid, and can be used for delivery of mRNA in lipid nanoparticles (LNPs) .
Art. -Nr.: HY-172332
CAS. Nr.: 3097638-09-7
Forschungsgebiete:
H1L1A1B3 is an ionizable cationic lipid used in the formation of lipid nanoparticles (LNPs) for the delivery of circular RNA (circRNA). H1L1A1B3-LNPs demonstrates a fourfold increase in circRNA transfection efficiency in lung cancer cells over ALC-0315 (HY-138170). H1L1A1B3 can activate the NF-κB/IRF immune pathways [1].
Art. -Nr.: HY-172771
Target:
Forschungsgebiete:
Multi-target kinase inhibitor 4 (Compound 2) is a PI3K/DNA-PK inhibitor and potent chemosensitizer that can increase the amount of DNA double strand breaks induced by Doxorubicin (HY-15142A). Multi-target kinase inhibitor 4, is an efficient inhibitor of multidrug resistance (MDR) that exhibits inhibitory activity toward P-glycoprotein-mediated drug efflux. Multi-target kinase inhibitor 4 can be loaded into PEG-coated LNPs .
Art. -Nr.: HY-165604
CAS. Nr.: 2639634-82-3
C14-490, an ionizable cationic lipid (pKa = 5.94), is used for the synthesis of lipid nanoparticles (LNPs). C14-490 LNPs is used as the basis for subsequent study of in utero gene editing in HSCs. C14-490 LNPs are used to encapsulate SpCas9 mRNA and TTR sgRNA using optimized B5 formulation parameters and surface conjugation to CD45 antibody F(ab’)2 fragments-Systematically optimized Targeted Editing Machinery LNPs (STEM LNPs) .
Art. -Nr.: HY-185778
CAS. Nr.: 3027931-27-4
PBA-Q76-O16B is a lipid that cannot cross the blood-brain barrier on its own, but can mediate cargo delivery into the brains of mice when blended with NT1 lipids. After forming stable small-sized lipid nanoparticles with NT1-O12B, PBA-Q76-O16B delivers drugs into the brains of mice. When formulated into lipid nanoparticles with NT1-O14B, PBA-Q76-O16B delivers (-27) GFP-Cre recombinase into mouse brain cells, driving functional gene recombination in multiple brain regions. PBA-Q76-O16B can be used in studies related to lipid nanoparticles (LNPs) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
