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MG5 cells

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-118828B
    12-Oxo phytodienoic acid (≥90%)
    1 Publications Verification

    12-OPDA (≥90%)

    		 NF-κB p38 MAPK TNF Receptor Interleukin Related NO Synthase Keap1-Nrf2 Neurological Disease Inflammation/Immunology
    12-Oxo phytodienoic acid (≥90%) (12-OPDA (≥90%)) is a plant lipid-derived anti-inflammatory compound. 12-Oxo phytodienoic acid (≥90%) induces the expression of SOCS-1 and inhibits LPS (HY-D1056)-induced activation of the NF-κB and p38 MAPK signaling pathways. 12-Oxo phytodienoic acid (≥90%) inhibits LPS-induced expression of IL-6 and TNF-α, and reduces LPS-induced NO production by decreasing iNOS levels. 12-Oxo phytodienoic acid (≥90%) induces activation of the Nrf2 signaling cascade. 12-Oxo phytodienoic acid (≥90%) can be used for the research of neurodegenerative diseases .
    12-Oxo phytodienoic acid (≥90%)

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