85551-10-6
Chemical Structure
12-Oxo phytodienoic acid
Synonym(s): 12-OPDA
- CAS. Nr.: 85551-10-6
- Formula:C18H28O3
- Molecular Weight:292.41
IUPAC Name: 8-((1S,5S)-4-oxo-5-((Z)-pent-2-en-1-yl)cyclopent-2-en-1-yl)octanoic acid
InChIKey: PMTMAFAPLCGXGK-JMTMCXQRSA-N
SMILES: O=C(O)CCCCCCC[C@H]1C=CC([C@H]1C/C=C\CC)=O
Biological Activity: 12-Oxo phytodienoic acid (12-OPDA) is a plant lipid-derived anti-inflammatory compound. 12-Oxo phytodienoic acid suppresses neuroinflammation by inhibiting Nf-κB and p38 MAPK signaling in Lipopolysaccharides (LPS) (HY-D1056)-activated cells. 12-Oxo phytodienoic acid can be used for neurodegenerative diseases research[1].
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12-Oxo phytodienoic acid | 12-Oxo phytodienoic acid (12-OPDA) is a plant lipid-derived anti-inflammatory compound. 12-Oxo phytodienoic acid suppresses neuroinflammation by inhibiting Nf-κB and p38 MAPK signaling in Lipopolysaccharides (LPS) (HY-D1056)-activated cells. 12-Oxo phytodienoic acid can be used for neurodegenerative diseases research. | |||||||||||||||||||||
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12-Oxo phytodienoic acid (≥90%) | 95.54% | 12-Oxo phytodienoic acid (≥90%) (12-OPDA (≥90%)) is a plant lipid-derived anti-inflammatory compound. 12-Oxo phytodienoic acid (≥90%) induces the expression of SOCS-1 and inhibits LPS (HY-D1056)-induced activation of the NF-κB and p38 MAPK signaling pathways. 12-Oxo phytodienoic acid (≥90%) inhibits LPS-induced expression of IL-6 and TNF-α, and reduces LPS-induced NO production by decreasing iNOS levels. 12-Oxo phytodienoic acid (≥90%) induces activation of the Nrf2 signaling cascade. 12-Oxo phytodienoic acid (≥90%) can be used for the research of neurodegenerative diseases. The product specifications provided below refer solely to the active content of 12-Oxo phytodienoic acid. |
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Similarity Score 1.00
HY-118828A(9S,13R)-12-Oxo phytodienoic acid -
Similarity Score 0.94
HY-116752Dinor-12-oxo phytodienoic acid -
Similarity Score 0.83
HY-164961OPC-8:0 -
Similarity Score 0.82
HY-11346113,14-Dihydro-15-keto-prostaglandin A2 -
Similarity Score 0.80
HY-23201A1-Phytoprostane-I -
Similarity Score 0.79
HY-N1548313,14-Dihydro-15-keto prostaglandin J2 -
Similarity Score 0.78
HY-13702415-Keto-PGA1 -
Similarity Score 0.77
HY-113053Prostaglandin A1 -
Similarity Score 0.77
HY-1145998-iso Prostaglandin A1 -
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