2 Results for "

MNK-45

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "MNK-45" in MCE Product Catalog:

  • Targets Recommended:
24
24 Cited Publications
Cat. No.: HY-115760
CAS No.: 175522-42-6
Target:  

Phosphatase

Research Areas:  

Neurological Disease Cancer

Okadaic acid ammonium salt, a marine toxin, is an inhibitor of protein phosphatases (PP). Okadaic acid ammonium salt has a significantly higher affinity for PP2A (IC50=0.1-0.3 nM), and inhibits PP1 (IC50=15-50 nM), PP3 (IC50=3.7-4 nM), PP4 (IC50=0.1 nM), PP5 (IC50=3.5 nM), but does not inhibit PP2C. Okadaic acid ammonium salt increases of phosphorylation of a number of proteins by inhibiting PP, and acts as a tumor promoter. Okadaic acid ammonium salt induces tau phosphorylation .
loading...
    loading...
Cat. No.: HY-157387
Target:  

c-Met/HGFR Apoptosis

Research Areas:  

Cancer

c-Met-IN-22 (compound 51am) is an orally active inhibitor against c-Met with an IC50 value of 2.54 nM. c-Met-IN-22 has antiproliferative and antitumor activities. c-Met-IN-22 induces cell apoptosis .
loading...
    loading...