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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
14 Results for "
Mertansine
" in MedChemExpress (MCE) Product Catalog:
Products (14)
14 Results for "Mertansine" in MCE Product Catalog:
28
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Mertansine (DM1) is a microtubulin inhibitor and is an antibody-conjugatable maytansinoid that is developed to overcome systemic toxicity associated with maytansine and to enhance tumor-specific delivery. Mertansine can be attached to a monoclonal antibody with a linker to create an antibody-drug conjugate (ADC) .
Cat. No.: HY-P99372
CAS No.: 339306-30-8
Synonyms: Anti-NCAM1/ CD56 Reference Antibody (lorvotuzumab)
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Cat. No.: HY-P99967
CAS No.: 1204740-23-7
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Cat. No.: HY-132262
CAS No.: 1008106-64-6
Synonyms: IMGN-901; BB-1090
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Lorvotuzumab mertansine is an ADC consisting of a humanized N901 monoclonal antibody against CD56 bound to maytansinoid DM1 via a stable disulfide linker. Lorvotuzumab mertansine has antitumor activity .
Cat. No.: HY-P99492
CAS No.: 400010-39-1
Synonyms: SB-408075; huC242-DM1
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SC-VC-PAB-DM1 is a agent-linker conjugate for ADC with with potent antitumor activity by using DM1 (Mertansine, a tubulin inhibitor) , linked via the ADC linker SC-VC-PAB .
Cat. No.: HY-164763
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SHR-A1201 is a HER2-targeting antibody-drug conjugate (ADC). SHR-A1201 is composed of a humanized anti-HER2 antibody (HY-P9907), a linker SMCC (HY-42360), and a microtubulin inhibitor payload Mertansine (HY-19792). SHR-A1201 can be used for research in HER2-positive breast cancer .
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DBCO-PEG4-Ahx-DM1 is a agent-linker conjugate composed of a potent microtubulin inhibitor DM1 and a linker DBCO-PEG4-Ahx to make antibody agent conjugate (ADC). Mertansine (DM1) is a microtubulin inhibitor and is an antibody-conjugatable maytansinoid that is developed to overcome systemic toxicity associated with maytansine and to enhance tumor-specific delivery. DBCO-PEG4-Ahx-DM1 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
Cat. No.: HY-W757436
Cat. No.: HY-48703
CAS No.: 936481-22-0
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DM1 Impurity is the impurity of Mertansine (DM1) (HY-19792) .
Cat. No.: HY-19792S2
Synonyms: DM1-d3; Maytansinoid DM1-d3
Cat. No.: HY-19792S
Synonyms: DM1-13C,d3; Maytansinoid DM1-13C,d3
Cat. No.: HY-P81055
Synonyms: Mertansine, Maytansinoid DM1, DM 1, 139504-50-0
Cat. No.: HY-P991874
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
