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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
11 Results for "
NAD-dependent enzyme
" in MedChemExpress (MCE) Product Catalog:
Products (11)
11 Results for "NAD-dependent enzyme" in MCE Product Catalog:
105
105 Cited Publications
Research Areas:
3-TYP is an inhibitor of SIRT3 (IC50of 38 μM) and an inhibitor of Methionine Adenosyltransferase (MAT) 2 and Indoleamine 2,3-Dioxygenase (IDO). There may be many off-target sites for 3-TYP that need to be examined, such as NAD-dependent enzymes, including dehydrogenases .
Research Areas:
α-NAD (α-Nicotinamide Adenine Dinucleotide) serves as a substrate for reninase, functions as an analog of β-NAD, affects the kinetics of NAD-dependent enzymes, and also plays a critical role as a cofactor in mitochondrial redox reactions .
Cat. No.: HY-E70020
UDP-Glc dehydrogenase (UGDH) catalyzes is a NAD+-dependent enzyme that catalyzes the two-fold oxidation of UDP-glucose (UDP-Glc) to produce UDP-glucuronic acid. UDP-Glc dehydrogenase (UGDH) is a key enzyme in the nucleotide-sugar interconversion pathway necessary for biosynthesis of many cell-wall polysaccharides .
Cat. No.: HY-P71918A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ME2; NAD-ME; Malic enzyme 2; Pyruvic-Malic Carboxylase; NAD-dependent Malic enzyme, Mitochondrial; Malic enzyme; Malate Dehydrogenase (Oxaloacetate-Decarboxylating); Cadherin; Malic enzyme 2, NAD(+)-dependent, Mitochondrial; ODS1
Cat. No.: HY-E71746
Target:
Research Areas:
3-Hydroxyisobutyrate dehydrogenase (EC 1.1.1.31) is a tetrameric mitochondrial enzyme that catalyzes the NAD+-dependent, reversible oxidation of 3-hydroxyisobutyrate, an intermediate of valine catabolism, to methylmalonate semialdehyde.
Cat. No.: HY-E71755
Target:
Research Areas:
3-Isopropylmalate dehydrogenase (EC 1.1.1.85) is an NAD+-dependent oxidoreductase involved in the leucine biosynthetic pathway. It catalyzes the oxidative decarboxylation of 3-isopropylmalate and is a key enzyme in leucine synthesis.
Cat. No.: HY-E71043
Target:
Research Areas:
D-2-Hydroxyglutarate Dehydrogenase, Acidaminococcus fermentans (EC 1.1.99.39) is a special NAD-dependent enzyme which reacts with D2HG specifically and converts D-2-hydroxyglutarate (D2HG) to α-ketoglutarate.
Target:
Research Areas:
L-Lactaldehyde ((2S)-Hydroxypropanal) is a chiral aldehyde, metabolic intermediate, and enzyme substrate. L-Lactaldehyde is oxidized to L-lactate by NAD-dependent lactaldehyde dehydrogenase. L-Lactaldehyde is reduced to L-1,2-propanediol by NADH/NADPH-dependent oxidoreductases. L-Lactaldehyde is used in studies of microbial sugar metabolism and carbonyl metabolism .
Cat. No.: HY-108331R
CAS No.: 120241-79-4
Target:
Reference Standards Sirtuin Methionine Adenosyltransferase (MAT) Indoleamine 2,3-Dioxygenase (IDO)
Research Areas:
3-TYP (Standard) is the analytical standard of 3-TYP (HY-108331). This product is intended for research and analytical applications. 3-TYP is an inhibitor of SIRT3 (IC50of 38 μM) and an inhibitor of Methionine Adenosyltransferase (MAT) 2 and Indoleamine 2,3-Dioxygenase (IDO). There may be many off-target sites for 3-TYP that need to be examined, such as NAD-dependent enzymes, including dehydrogenases .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
