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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
7 Results for "
NBC1
" in MedChemExpress (MCE) Product Catalog:
Products (7)
7 Results for "NBC1" in MCE Product Catalog:
Cat. No.: HY-165407
CAS No.: 99453-84-6
Target:
Research Areas:
Neltenexine is a mucolytic agent and an inhibitor of anion hypersecretion. Neltenexine acts on NKCC1, NBC1 and AE2 transporters located on the basolateral membrane of airway epithelial cells . Neltenexine reduces Cl -/HCO3 - uptake by inhibiting NKCC1 and NBC1, activates AE2 to promote Cl - excretion, reduces β2-adrenergic agonist-induced anion hypersecretion without blocking CFTR channels, and maintains appropriate airway fluid levels . Neltenexine can be used in research related to chronic obstructive pulmonary disease and emphysema [1] .
Cat. No.: HY-165407A
CAS No.: 99461-80-0
Target:
Research Areas:
Neltenexine hydrochloride is a mucolytic agent and an inhibitor of anion hypersecretion. Neltenexine hydrochloride acts on NKCC1, NBC1 and AE2 transporters located on the basolateral membrane of airway epithelial cells . Neltenexine hydrochloride reduces Cl -/HCO3 - uptake by inhibiting NKCC1 and NBC1, activates AE2 to promote Cl - excretion, reduces β2-adrenergic agonist-induced anion hypersecretion without blocking CFTR channels, and maintains appropriate airway fluid levels . Neltenexine hydrochloride can be used in research related to chronic obstructive pulmonary disease and emphysema [1] .
Cat. No.: HY-P703252
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: SLC4A4; Pancreatic Sodium Bicarbonate Cotransporter; Prev. SLC4A5; Na(+)/HCO3(-) Cotransporter; KNBC1; Sodium Bicarbonate Cotransporter 1 (Sodium Bicarbonate Cotransporter, Kidney; Sodium Bicarbonate Cotransporter, Pancreas); NBC1; Solute Carrier Family 4
Cat. No.: HY-RS25564
Target:
Research Areas:
Slc4a4 Rat Pre-designed siRNA Set A contains three designed siRNAs for Slc4a4 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS13270
Target:
Research Areas:
SLC4A4 Human Pre-designed siRNA Set A contains three designed siRNAs for SLC4A4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P89587
Synonyms: NBC, NBC1, NBCE1, SLC4A4, Electrogenic sodium bicarbonate cotransporter 1, Sodium bicarbonate cotransporter, Na(+)/HCO3(-) cotransporter, Solute carrier family 4 member 4, kNBC1
Cat. No.: HY-RS19074
Target:
Research Areas:
Slc4a4 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Slc4a4 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
