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Results for "

NCK2

" in MedChemExpress (MCE) Product Catalog:

5

Inhibitors & Agonists

2

Natural
Products

2

Antibodies

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N0710
    alpha-Cyperone
    3 Publications Verification

    α-Cyperone; (+)-α-Cyperone

    		 Endogenous Metabolite Inflammation/Immunology
    alpha-Cyperone (α-Cyperone) is associated with the down-regulation of COX-2, IL-6, Nck-2, Cdc42 and Rac1, resulting in reduction of inflammation, which would be highly beneficial for treatment of inflammatory diseases such as AD.
    alpha-Cyperone
  • HY-173156
    UNC10013

    		Histone Methyltransferase Cancer
    UNC10013 is an inhibitor targeting the triple Tudor domain (3TD) of SETDB1. UNC10013 covalently binds to Cys385 of SETDB1 3TD, acts as a negative allosteric modulator of the methyltransferase domain of SETDB1, reduces the level of Akt methylation mediated by SETDB1, and blocks Tyr308 phosphorylation of Akt. UNC10013 is applicable to cancer-related research .
    UNC10013
  • HY-RS09081
    NCK2 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    NCK2 Human Pre-designed siRNA Set A contains three designed siRNAs for NCK2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    NCK2 Human Pre-designed siRNA Set A
    NCK2 Human Pre-designed siRNA Set A
  • HY-N0710R
    alpha-Cyperone (Standard)

    α-Cyperone (Standard); (+)-α-Cyperone (Standard)

    		 Reference Standards Endogenous Metabolite Inflammation/Immunology
    alpha-Cyperone (Standard) is the analytical standard of alpha-Cyperone. This product is intended for research and analytical applications. alpha-Cyperone (α-Cyperone) is associated with the down-regulation of COX-2, IL-6, Nck-2, Cdc42 and Rac1, resulting in reduction of inflammation, which would be highly beneficial for treatment of inflammatory diseases such as AD.
    alpha-Cyperone (Standard)
  • HY-171744
    CX-5279

    		Casein Kinase Cancer
    CX-5279 is an efficient and selective CK2 inhibitor with IC50 values for nCK2 and CK2α of 2.73 and 0.91 nM, respectively. CX-5279 is sensitive to mutations at Val66, Ile174, and V66I174AA, with IC50 values of 13.8, 12.5, and 23.35 nM, respectively. CX-5279's inhibitory activity against PIM1 is very weak, with a IC50 value of 8.52 μM. CX-5279 exhibits anti-proliferative activity in various cancer cell lines. CX-5279 can be used for research on cancers such as pancreatic cancer and leukemia .
    CX-5279

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