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NPL4

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Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W111581
    Copper(II) diethyldithiocarbamate
    1 Publications Verification

    Diethyldithiocarbamic acid copper salt

    Apoptosis Caspase Cancer
    Copper(II) diethyldithiocarbamate (Diethyldithiocarbamic acid copper salt) is a Copper(II) and diethyldithiocarbamate coordination polymer. Copper(II) diethyldithiocarbamate binds tightly to NPL4 and induces its aggregation, disrupting the p97-NPL4-UFD1 pathway. Copper(II) diethyldithiocarbamate causes ubiquitinated proteins accumulation and impairs waste proteins degradation, thus resulting in cell apoptosis. Copper(II) diethyldithiocarbamate inhibits tumor growth in MDA-MB-231 xenograft mice models. Copper(II) diethyldithiocarbamate can be used for the research of cancer, such as breast cancer .
    Copper(II) diethyldithiocarbamate
  • HY-RS09489

    Small Interfering RNA (siRNA) Others

    NPLOC4 Human Pre-designed siRNA Set A contains three designed siRNAs for NPLOC4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    NPLOC4 Human Pre-designed siRNA Set A
    NPLOC4 Human Pre-designed siRNA Set A

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