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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
10 Results for "
NR3C1
" in MedChemExpress (MCE) Product Catalog:
Products (10)
10 Results for "NR3C1" in MCE Product Catalog:
Cat. No.: HY-RS09545
Target:
Research Areas:
Nr3c1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Nr3c1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Triphenyl phosphate is an orally active, blood-brain barrier-permeable aryl organophosphate flame retardant and endocrine disruptor. Triphenyl phosphate disrupts mitochondrial dynamic balance through oxidative stress, induces excessive mitophagy and apoptosis, and ultimately leads to myocardial fibrosis. In the brain, Triphenyl phosphate activates the NF-κB inflammatory pathway by disrupting the gut microbiota, alters tryptophan metabolism and elevates neurotoxins, thereby inducing anxiety- and depression-like behaviors. In the skeletal and reproductive systems, Triphenyl phosphate inhibits osteoblast differentiation and induces germ cell apoptosis by suppressing the MAPK/ERK pathway and activating the JNK signal, respectively. In adipose and placental tissues, Triphenyl phosphate promotes lipid accumulation by activating the PI3K/AKT-PPARγ axis, and disrupts placental metabolism via the MAOA/ROS/NF-κB cascade, impairing neurodevelopment of offspring .
Cat. No.: HY-RS09544
Target:
Research Areas:
NR3C1 Human Pre-designed siRNA Set A contains three designed siRNAs for NR3C1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS09546
Target:
Research Areas:
Nr3c1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Nr3c1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P702781
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: NR3C1; Nuclear Receptor Subfamily 3 Group C Member 1 Variant HGR-B(77); Prev. GRL; GCR; GR; Nuclear Receptor Subfamily 3, Group C, Member 1; Glucocorticoid Receptor; Alternative Protein NR3C1; Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoi
Cat. No.: HY-P86539
Synonyms: GCCR; GCR; GCR_HUMAN; GCRST; glucocorticoid nuclear receptor variant 1; Glucocorticoid receptor; GR; GRL; Grl1; NR3C1; Nuclear receptor subfamily 3 group C member 1; nuclear receptor subfamily 3, group C, member 1; glucocorticoid receptor;
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
