2 Results for "

PDI-IN-2

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "PDI-IN-2" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-142127
CAS No.: 25546-65-0
Synonyms: VistamycIN; SF-733
Ribostamycin (Vistamycin) is a broad-spectrum aminoglycoside antibiotic. Ribostamycin is effective against Gram-Negative and Gram-Positive bacterial infection. Ribostamycin also inhibits the chaperone activity of PDI .
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Cat. No.: HY-163351
Research Areas:  

Cardiovascular Disease Cancer

PDI-IN-2 is a highly selective PDI inhibitor. PDI-IN-2 has an IC50 of 0.63-4.01 μM against human PDI, and exhibits higher targeting specificity compared with ERp57 and ERp72. PDI-IN-2 inhibits platelet aggregation induced by U46619, collagen and tumor cells, and also blocks platelet-promoted tumor cell proliferation as well as the growth of multiple myeloma cells. PDI-IN-2 serves as an important tool reagent for research on multiple myeloma and associated thrombosis .
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