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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
6 Results for "
PROTAC K-Ras Degrader-4
" in MedChemExpress (MCE) Product Catalog:
Products (6)
6 Results for "PROTAC K-Ras Degrader-4" in MCE Product Catalog:
Cat. No.: HY-159788
CAS No.: 2938169-99-2
PROTAC K-Ras Degrader-4 (Compound 4) is a PROTAC degrader for KRAS that degrades KRAS G12D in GP5d and degrades KRAS G12V in cell SW620 with DC50s of 1 nM and 13 nM. PROTAC K-Ras Degrader-4 inhibits MAPK signaling pathway .
Cat. No.: HY-153674
PROTAC SOS1 degrader-4 (Compound 10) is a PROTAC degrader that targets the SOS1 protein for degradation by recruiting cereblon. It degrades SOS1 in NCI-H358, A-427, SW-620, and DLD-1 cells and inhibits the proliferation of various KRAS-mutant tumor cells, making it a useful tool for cancer research .
Cat. No.: HY-168671
CAS No.: 2886012-31-1
Research Areas:
pan-KRAS ligand 1 is a Ligand for Target Protein for PROTAC. pan-KRAS ligand 1 can be used for synthesis PROTAC pan-KRAS degrader 4 (HY-168669) .
Cat. No.: HY-159790
Target:
Research Areas:
Methyl (R)-2-(3-(4-bromobutoxy)isoxazol-5-yl)-3-methylbutanoate is a PROTAC linker that can be used for the synthesis of PROTACs, such as PROTAC K-Ras Degrader-4 (HY-159788) .
Cat. No.: HY-175575
CAS No.: 3027979-08-1
Research Areas:
SOS1 ligand-2 is a SOS1 ligand that can be used for PROTAC synthesis. SOS1 ligand-2 serves as the target protein ligand for PROTAC SOS1 degrader-4 (HY-153674). SOS1 ligand-2 is applicable to the research of KRAS-mutant cancers .
Cat. No.: HY-168672
CAS No.: 3052750-99-6
Research Areas:
E3 Ligase Ligand-linker Conjugate 133 is a conjugate of E3 ligase ligand and linker that serve as a key intermediate for the synthesis of complete PROTAC molecule pan-KRAS degrader 4 (HY-168669) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
