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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
8 Results for "
PTPN12
" in MedChemExpress (MCE) Product Catalog:
Products (8)
8 Results for "PTPN12" in MCE Product Catalog:
Cat. No.: HY-RS11417
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PTPN12 Human Pre-designed siRNA Set A contains three designed siRNAs for PTPN12 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS19808
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Ptpn12 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ptpn12 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS26304
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Ptpn12 Rat Pre-designed siRNA Set A contains three designed siRNAs for Ptpn12 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
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LYP-IN-3 is a selective, orally active and reversible lymphoid-tyrosine phosphatase (LYP) inhibitor (IC50 = 2.55 μM, Ki = 0.93 μM). D34 exhibits high selectivity of PTP1B, PTPN12, PTPN5 and SSH2. LYP-IN-3 regulates the T-cell receptor (TCR) signaling by specifically inhibiting LYP. LYP-IN-3 does not significantly inhibit MC38 cell viability; its anti-tumor effect stems from immune regulation. LYP-IN-3 can significantly upregulate PD-L1 or PD-1 expression in different immune cells. LYP-IN-3 facilitates T-cell infiltration and enhances T-cell functions. LYP-IN-3 synergizes with PD-L1 blockade can significantly improve colorectal tumor regression. LYP-IN-3 can be used for the study of colorectal cancer .
Cat. No.: HY-P76557
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: Tyrosine-protein phosphatase non-receptor type 12; PTP-PEST; PTPG1
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Cat. No.: HY-P76558
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Tyrosine-protein phosphatase non-receptor type 12; PTP-PEST; PTPG1
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Cat. No.: HY-P11604
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
