PTPN12 Antibody
(Synonyms: Tyrosine-protein phosphatase non-receptor type 12, PTP-PEST, Protein-tyrosine phosphatase G1, PTPG1, PTPN12)PTPN12 Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to PTPN12.
-
Host:
Rabbit
-
Isotype:
IgG
-
Application:
WB
-
Formulation:
Supplied in PBS(pH 7.3), 30% glycerol, and 0.01% sodium azide.
-
Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
|
|---|---|
| Dilution Ratio | 1:1000-2000 |
Product Details
PTPN12 Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to PTPN12.
-
Host Rabbit
-
Clonality Polyclonal
-
Calculated Molecular Weight Predicted band size: 88kDa;
KLH conjugated synthetic peptide derived from human PTPN12
Endogenous
affinity purified by Protein A
Non-conjugated
Unmodified
IgG
Product Properties
-
Appearance
Solution
-
Formulation
Supplied in PBS(pH 7.3), 30% glycerol, and 0.01% sodium azide.
-
Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
-
Shipping
Shipping with blue ice.
Background
-
Function
PTPN12 dephosphorylates a range of proteins, and thereby regulates cellular signaling cascades. Dephosphorylates cellular tyrosine kinases, such as ERBB2 and PTK2B/PYK2, and thereby regulates signaling via ERBB2 and PTK2B/PYK2. Selectively dephosphorylates ERBB2 phosphorylated at 'Tyr-1112', 'Tyr-1196', and/or 'Tyr-1248'[1][2][3].
-
Subcellular Localization
Cytoplasm,Cell junction, focal adhesion,Cell projection, podosome
-
Isoforms & Post-Translational Modification
Q05209 has three isomers: Q05209-1: 88106 Da (predicted); Q05209-2: 72778 Da (predicted); Q05209-3: 74138 Da (predicted).
Phosphorylated by STK24/MST3 and this results in inhibition of its activity -
Subunit
Interacts with TGFB1I1 (By similarity)
-
SwissProt ID
-
Synonyms
Tyrosine-protein phosphatase non-receptor type 12, PTP-PEST, Protein-tyrosine phosphatase G1, PTPG1, PTPN12
Documentation
Powered by Bioz
