2 Results for "

PfKRS1

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "PfKRS1" in MCE Product Catalog:

Cat. No.: HY-136767
CAS No.: 35818-31-6
Purity:  99.90%
Cladosporin is an antibiotic and an an antifungal metabolite that can be produced in good yield in the mycelium of Cladosporium cladosporioid. Cladosporin exhibits inhibitory activity against various dermatophytes, plant pathogens, and bacteria. Cladosporin also exhibits antimalarial activity through inhibition of cytoplasmic lysine-tRNA synthetase of Plasmodium (PfKrs1) [1] .
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Cat. No.: HY-184406
Target:  

Parasite

Research Areas:  

Infection

Antimalarial agent 65 is an inhibitor of Plasmodium falciparum lysyl-tRNA synthetase (PfKRS1), with a pIC50 value of 6.9 against Plasmodium falciparum. Antimalarial agent 65 inhibits the growth of Plasmodium falciparum strains. Antimalarial agent 65 exhibits activity across multiple life cycle stages of the malaria parasite, including transmission-blocking activity. Antimalarial agent 65 can be used in malaria-related research [1].
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