35818-31-6
Chemical Structure
Cladosporin
- CAS No.: 35818-31-6
- Formula:C16H20O5
- Molecular Weight:292.33
IUPAC Name: (R)-6,8-dihydroxy-3-(((2R,6S)-6-methyltetrahydro-2H-pyran-2-yl)methyl)isochroman-1-one
InChIKey: WOMKDMUZNBFXKG-ZWKOPEQDSA-N
SMILES: O=C1C2=C(O)C=C(O)C=C2C[C@H](C[C@H]3CCC[C@H](C)O3)O1
Biological Activity: Cladosporin is an antibiotic and an an antifungal metabolite that can be produced in good yield in the mycelium of Cladosporium cladosporioid. Cladosporin exhibits inhibitory activity against various dermatophytes, plant pathogens, and bacteria. Cladosporin also exhibits antimalarial activity through inhibition of cytoplasmic lysine-tRNA synthetase of Plasmodium (PfKrs1)[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Cladosporin | 99.90% | Cladosporin is an antibiotic and an an antifungal metabolite that can be produced in good yield in the mycelium of Cladosporium cladosporioid. Cladosporin exhibits inhibitory activity against various dermatophytes, plant pathogens, and bacteria. Cladosporin also exhibits antimalarial activity through inhibition of cytoplasmic lysine-tRNA synthetase of Plasmodium (PfKrs1). | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
- [1]. P M Scott, et al. Cladosporin, a new antifungal metabolite from Cladosporium cladosporioides. J Antibiot (Tokyo). 1971 Nov;24(11):747-55. [Content Brief]
- [2]. Hoepfner D, et al., Selective and specific inhibition of the plasmodium falciparum lysyl-tRNA synthetase by the fungal secondary metabolite cladosporin. Cell Host Microbe. 2012 Jun 14;11(6):654-63. [Content Brief]
Keywords
