Lasiodiplodin
Lasiodiplodin is a potent anti-leukemic macrolide can be isolated from Euphorbia splendens.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 32885-81-7
- 分子式: C17H24O4
- 分子量:292.37
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
製品説明
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| BV-2 | IC50 |
>100 μM
Compound: 10
|
Inhibition of LPS-induced nitric oxide production in mouse BV2 cells pretreated for 1 hr before LPS stimulation measured after 24 hrs by Griess assay
Inhibition of LPS-induced nitric oxide production in mouse BV2 cells pretreated for 1 hr before LPS stimulation measured after 24 hrs by Griess assay
|
[PMID: 27592135] |
| U-937 | IC50 |
20 μM
Compound: 32, lasiodiplodin
|
Antiproliferative activity against human U937 cells after 72 hrs by WST-8 assay
Antiproliferative activity against human U937 cells after 72 hrs by WST-8 assay
|
[PMID: 17158054] |
| U-937 | IC50 |
28 μM
Compound: 32, lasiodiplodin
|
Antiproliferative activity against human U937 cells after 48 hrs by WST-8 assay
Antiproliferative activity against human U937 cells after 48 hrs by WST-8 assay
|
[PMID: 17158054] |
| U-937 | IC50 |
36 μM
Compound: 32, lasiodiplodin
|
Antiproliferative activity against human U937 cells after 24 hrs by WST-8 assay
Antiproliferative activity against human U937 cells after 24 hrs by WST-8 assay
|
[PMID: 17158054] |
化学情報
-
CAS 番号 32885-81-7
-
分子量 292.37
-
分子式 C17H24O4
-
SMILES
COC1=C2C(CCCCCCC[C@@H](OC2=O)C)=CC(O)=C1
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Structure Classification
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Initial Source
endophytic fungus
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輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)