2 Results for "

Pheophytin

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "Pheophytin" in MCE Product Catalog:

Pheophytin a
Pheophytin a
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Art. -Nr.: HY-N12586
CAS. Nr.: 603-17-8
Category:  

Suaeda vermiculata Forssk. ex J.F.Gmel. Alkaloids Other Alkaloids Amaranthaceae Plants

Target:  

ERK Reactive Oxygen Species (ROS) COX PGE synthase STAT HCV HCV Protease

Pheophytin a is a multi-target inhibitor, anticancer agent, antioxidant and antiviral agent. Pheophytin a directly binds to and inhibits HCV-NS3/4A protease (IC50=0.89 μM) to block viral replication. Pheophytin a also scavenges free radicals, reduces ferric ions, and exhibits cytotoxic activity against breast cancer cells. Pheophytin a effectively inhibits LPS-induced production of nitric oxide, prostaglandin E2, NOS2 and COX-2, as well as various pro-inflammatory cytokines, by downregulating the transcription levels of inflammatory mediators and blocking the ERK1/2 and STAT-1 pathways. In a low nerve growth factor environment, Pheophytin a also enhances ERK1/2 phosphorylation and synergistically promotes neurite outgrowth through MAPK pathway. Pheophytin a can be used to investigate the pathogenic mechanisms of diseases including chronic hepatitis C, sepsis, breast cancer and Alzheimer's disease .
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Chlorophyllase
Chlorophyllase
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Art. -Nr.: HY-E70911
Target:  

Biochemical Assay Reagents

Forschungsgebiete:  

Others

Chlorophyllase (EC 3.1.1.14) is part of the chlorophyll degradation pathway and is believed to be involved in various plant chlorosis processes, such as fruit ripening, leaf senescence, and flowering, as well as chlorophyll turnover and homeostasis. Chlorophyllase (EC 3.1.1.14) preferentially acts on chlorophyll a, but can also use chlorophyll b and pheophytin as substrates.
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