4 Results for "

Poly(U)

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "Poly(U)" in MCE Product Catalog:

Poly(U)
Poly(U)
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Cat. No.: HY-131920
CAS No.: 27416-86-0
Synonyms: Polyuridylic acid
Poly (U) (Polyuridylic acid) is an RNA chain that exists in a disordered extended state at room temperature and serves as a TLR7 ligand. Poly (U) produces distinguishable blocking effects when transported through α-hemolysin nanopores. Poly (U) forms a triple helix with adenosine or adenosine monophosphate, thereby significantly promoting the nucleotide bond condensation reaction between adenosine monophosphate and adenosine, while exerting minimal effects on other nucleosides. When conjugated with cationic lipids, Poly (U) specifically stimulates plasmacytoid dendritic cells to produce type I interferons .
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Poly(U) potassium
Poly(U) potassium
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Cat. No.: HY-131920A
CAS No.: 28086-43-3
Synonyms: Polyuridylic acid potassium
Polyuridylic acid potassium is a polynucleotide. In protein synthesis systems based on active mammalian ribosomes, Polyuridylic acid potassium acts as a specific messenger to induce the biosynthesis of polyphenylalanine, with no effect on the incorporation of non-phenylalanine amino acids. Polyuridylic acid potassium serves as a template to promote the non-enzymatic synthesis of oligoadenylates .
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2'-Deoxy-2'-fluorouridine
2'-Deoxy-2'-fluorouridine
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Cat. No.: HY-W013403
CAS No.: 784-71-4
Target:  

IFNAR

Research Areas:  

Infection

2'-Deoxy-2'-fluorouridine is a derivative of the pyrimidine nucleoside uridine. 2'-Deoxy-2'-fluorouridine is a nucleoside analog that inhibits the replication of wild-type viruses by binding to the viral RNA. Hepatitis C polyU/UC RNA strands containing 2'-Deoxy-2'-fluorouridine, bind to RIG-I but do not activate RIG-I signaling in a reporter assay using Huh7 cells. 2'-Deoxy-2'-fluorouridine also has been used as a starting material in the synthesis of respiratory syncytial virus (RSV) polymerase inhibitors. 2'-Deoxy-2'-fluorouridine can incorporate into DNA and RNA in rat and woodchuck model upon administration. 2'-Deoxy-2'-fluorouridine can be studied in anti-viral research .
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2'-Deoxy-2'-fluorouridine-d2
2'-Deoxy-2'-fluorouridine-d2
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Cat. No.: HY-W013403S
CAS No.: 362049-50-1
2'-Deoxy-2'-fluorouridine-d2 is the deuterium labeled 2'-Deoxy-2'-fluorouridine . 2'-Deoxy-2'-fluorouridine is a derivative of the pyrimidine nucleoside uridine. 2'-Deoxy-2'-fluorouridine is a nucleoside analog that inhibits the replication of wild-type viruses by binding to the viral RNA. Hepatitis C polyU/UC RNA strands containing 2'-Deoxy-2'-fluorouridine, bind to RIG-I but do not activate RIG-I signaling in a reporter assay using Huh7 cells. 2'-Deoxy-2'-fluorouridine also has been used as a starting material in the synthesis of respiratory syncytial virus (RSV) polymerase inhibitors. 2'-Deoxy-2'-fluorouridine can incorporate into DNA and RNA in rat and woodchuck model upon administration. 2'-Deoxy-2'-fluorouridine can be studied in anti-viral research .
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