5 Results for "

R51211

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "R51211" in MCE Product Catalog:

24
Itraconazole
Itraconazole
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24 Cited Publications
Cat. No.: HY-17514
CAS No.: 84625-61-6
Synonyms: R51211
Category:  

Microorganisms

Target:  

Fungal Hedgehog Cytochrome P450 Autophagy Antibiotic Bacterial

Itraconazole (R51211) is a triazole antifungal agent and a potent and orally active Hedgehog (Hh) signaling pathway antagonist with an IC50 of ~800 nM. Itraconazole potently inhibits lanosterol 14α-demethylase (cytochrome P450 enzyme), thereby inhibits the oxidative conversion of lanosterol to ergosterol. Itraconazole has anticancer and antiangiogenic effects. Itraconazole is a oxysterol-binding protein (OSBP) inhibitor .
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Itraconazole-d5
Itraconazole-d5
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Cat. No.: HY-17514S
CAS No.: 1217510-38-7
Synonyms: R51211-d5
Itraconazole-d5 is the deuterium labeled Itraconazole. Itraconazole (R51211) is a triazole antifungal agent and a potent and orally active Hedgehog (Hh) signaling pathway antagonist with an IC50 of ~800 nM. Itraconazole potently inhibits lanosterol 14α-demethylase (cytochrome P450 enzyme), thereby inhibits the oxidative conversion of lanosterol to ergosterol. Itraconazole has anticancer and antiangiogenic effects .
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Itraconazole (Standard)
Itraconazole (Standard)
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Cat. No.: HY-17514R
CAS No.: 84625-61-6
Synonyms: R51211 (Standard)
Category:  

Microorganisms

Target:  

Reference Standards Fungal Hedgehog Cytochrome P450 Autophagy Antibiotic Bacterial

Itraconazole (Standard) is the analytical standard of Itraconazole. This product is intended for research and analytical applications. Itraconazole (R51211) is a triazole antifungal agent and a potent and orally active Hedgehog (Hh) signaling pathway antagonist with an IC50 of ~800 nM. Itraconazole potently inhibits lanosterol 14α-demethylase (cytochrome P450 enzyme), thereby inhibits the oxidative conversion of lanosterol to ergosterol. Itraconazole has anticancer and antiangiogenic effects. Itraconazole is a oxysterol-binding protein (OSBP) inhibitor .
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Itraconazole-d3
Itraconazole-d3
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Cat. No.: HY-17514S1
CAS No.: 1217512-35-0
Synonyms: R51211-d3
Itraconazole-d3 (R51211-d3) is the deuterium labeled Itraconazole (HY-17514) . Itraconazole (R51211) is a triazole antifungal agent and a potent and orally active Hedgehog (Hh) signaling pathway antagonist with an IC50 of ~800 nM. Itraconazole potently inhibits lanosterol 14α-demethylase (cytochrome P450 enzyme), thereby inhibits the oxidative conversion of lanosterol to ergosterol. Itraconazole has anticancer and antiangiogenic effects. Itraconazole is a oxysterol-binding protein (OSBP) inhibitor.
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Itraconazole-d9
Itraconazole-d9
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Cat. No.: HY-17514S2
CAS No.: 1309272-50-1
Synonyms: R51211-d9
Itraconazole-d9 is the deuterium labeled Itraconazole . Itraconazole (R51211) is a triazole antifungal agent and a potent and orally active Hedgehog (Hh) signaling pathway antagonist with an IC50 of ~800 nM. Itraconazole potently inhibits lanosterol 14α-demethylase (cytochrome P450 enzyme), thereby inhibits the oxidative conversion of lanosterol to ergosterol. Itraconazole has anticancer and antiangiogenic effects. Itraconazole is a oxysterol-binding protein (OSBP) inhibitor .
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