3 Results for "

RIVA

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "RIVA" in MCE Product Catalog:

Cat. No.: HY-156437
CAS No.: 2225902-98-5
Purity:  99.73%
Target:  

Apoptosis NEKs Mitosis Akt

Research Areas:  

Cancer

NBI-961 is a NEK2 catalytic inhibitor with human NEK2 IC50 ~12-fold lower than FLT3. NBI-961 induces proteasomal degradation of NEK2. NBI-961 induces G2/mitosis arrest, apoptosis, and compromises viability in DLBCL cells and patient-derived cells. NBI-961 sensitizes DLBCL cells to doxorubicin and vincristine, and suppresses DLBCL tumor growth in mice. NBI-961 can be used for the research of diffuse large b cell lymphoma .
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Cat. No.: HY-168190
Target:  

PROTACs

Research Areas:  

Cancer

PROTAC TBL1X degrader-1 is a TBL1X PROTAC degrader. PROTAC TBL1X degrader-1 induces TBL1X degradation via the Cereblon-mediated proteasomal pathway. PROTAC TBL1X degrader-1 exerts cytotoxic effects on cancer cells. PROTAC TBL1X degrader-1 can be used in studies related to diffuse large B-cell lymphoma .
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Cat. No.: HY-182706
CAS No.: 95455-02-0
Research Areas:  

Cancer

NSC 373981 is a CARD11 G4 stabilizer. NSC 373981 stabilizes the CARD11 G4 structure and inhibits CARD11 transcription in cells. NSC 373981 also inhibits BCL2 and MYC. NSC 373981 suppresses the transcription of KRAS and TERT. NSC 373981 exhibits anticancer activity against diffuse large B-cell lymphoma .
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