9 Results for "

Reduced Haloperidol

" in MedChemExpress (MCE) Product Catalog:
Products (9)

9 Results for "Reduced Haloperidol" in MCE Product Catalog:

Cat. No.: HY-107969
CAS No.: 74050-97-8
Purity:  99.67%
Research Areas:  

Neurological Disease Cancer

Haloperidol decanoate is a depot preparation of haloperidol, a commonly used butyrophenone derivative with antipsychotic activity. Haloperidol decanoate can increase the striatal D2 receptor in rat. Haloperidol decanoate can improve conditions of psychoses (mainly schizophrenia). Haloperidol decanoate can lead to increased accumulation of the dopamine metabolites homo-vanillic acid. Haloperidol decanoate can reduce intestinal transport, increase gastric emptying and reduce acid output in rat model .
loading...
    loading...
Cat. No.: HY-14866
CAS No.: 757950-09-7
Synonyms: ADX-10059
Target:  

mGluR

Research Areas:  

Neurological Disease

Raseglurant (ADX-10059) is a mGlu5 receptor negative allosteric modulator. Raseglurant is effective against migraine. Raseglurant reduces the Haloperidol (HY-14538)-induced catalepsy in mice .
loading...
    loading...
Cat. No.: HY-137546
CAS No.: 34104-67-1
Synonyms: Haloperidol metabolite II
Target:  

Drug Metabolite

Reduced Haloperidol (Haloperidol metabolite II) is an antipsychotic compound with neurotransmitter modulating activity. Reduced Haloperidol is commonly used to inhibit schizophrenia and other psychotic disorders. Reduced Haloperidol helps reduce the occurrence of hallucinations and delusions by inhibiting the activity of dopamine receptors.
loading...
    loading...
Cat. No.: HY-105879
CAS No.: 72808-81-2
Synonyms: HR-592 free base
Target:  

Drug Derivative

Research Areas:  

Neurological Disease

Tepirindole (HR-592 free base) is an orally active Indole (HY-W001132) derivative. Tepirindole reduces incidence of catalepsy induced by Haloperidol (HY-14538). Tepirindole suppresses the turning behavior induced by Methamphetamine .
loading...
    loading...
Cat. No.: HY-137546S
CAS No.: 1246820-79-0
Synonyms: Haloperidol metabolite II-d4
Reduced Haloperidol-d4 is the deuterium labeled Reduced Haloperidol .
loading...
    loading...
Cat. No.: HY-107969R
CAS No.: 74050-97-8
Haloperidol decanoate (Standard) is the analytical standard of Haloperidol decanoate. This product is intended for research and analytical applications. Haloperidol decanoate is a depot preparation of haloperidol, a commonly used butyrophenone derivative with antipsychotic activity. Haloperidol decanoate can increase the striatal D2 receptor in rat. Haloperidol decanoate can improve conditions of psychoses (mainly schizophrenia). Haloperidol decanoate can lead to increased accumulation of the dopamine metabolites homo-vanillic acid. Haloperidol decanoate can reduce intestinal transport, increase gastric emptying and reduce acid output in rat model .
loading...
    loading...
Cat. No.: HY-171472
CAS No.: 171961-95-8
Target:  

Dopamine Receptor

Research Areas:  

Neurological Disease

A-86929 is a highly potent and selective dopamine D1 receptor agonist with a pKi value of 7.3. In the 6-OHDA (HY-B1081)-induced unilateral nigrostriatal lesion rat model, A-86929 significantly induces rotational behavior. It also improves motor function in the MPTP (HY-15608)-induced Parkinson's disease marmoset model. Additionally, A-86929 demonstrates potential therapeutic value in reducing cocaine-seeking behavior in rats and reversing Haloperidol (HY-14538)-induced cognitive deficits in rhesus monkeys. A-86929 can be used for research in neurological disorders .
loading...
    loading...
Cat. No.: HY-W777360
CAS No.: 1189461-56-0
Harman- 13C2, 15N is 13C and 15N labeled Harmane. Harmane is a benzodiazepine receptor inhibitor (IC50=7 μM), with IC50 values for mACh, Opioid Receptor, MAO-A/B, and α2-adrenergic receptor of 24 μM, 2.8 μM, 0.5 μM, 5 μM, and 18 μM, respectively. Harmane also inhibits haloperidol and serotonin, with IC50 values of 163 μM and 101 μM, respectively. Harmane inhibits the I1 imidazoline receptor (IC50=30 nM) to reduce blood pressure and has antidepressant, anti-anxiety, anticonvulsant, and analgesic effects. Harmane inhibits dopamine biosynthesis by decreasing tyrosine hydroxylase (TH) activity and enhancing L-DOPA-induced cytotoxicity in PC12 cells. Additionally, Harmane can increase the mutagenic effect induced by 2-acetylaminofluorene (AAF) .
loading...
    loading...
Cat. No.: HY-W700834
CAS No.: 1216708-84-7
Harman-d3 is deuterium labeled Harmane. Harmane is a benzodiazepine receptor inhibitor (IC50=7 μM), with IC50 values for mACh, Opioid Receptor, MAO-A/B, and α2-adrenergic receptor of 24 μM, 2.8 μM, 0.5 μM, 5 μM, and 18 μM, respectively. Harmane also inhibits haloperidol and serotonin, with IC50 values of 163 μM and 101 μM, respectively. Harmane inhibits the I1 imidazoline receptor (IC50=30 nM) to reduce blood pressure and has antidepressant, anti-anxiety, anticonvulsant, and analgesic effects. Harmane inhibits dopamine biosynthesis by decreasing tyrosine hydroxylase (TH) activity and enhancing L-DOPA-induced cytotoxicity in PC12 cells. Additionally, Harmane can increase the mutagenic effect induced by 2-acetylaminofluorene (AAF) .
loading...
    loading...