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Reinnervation

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P2727
    Chondroitinase ABC
    2 Publications Verification

    ChABC

    		 Endogenous Metabolite Neurological Disease Inflammation/Immunology
    Chondroitinase ABC (ChABC) is an enzyme that degrades glycosaminoglycan side-chains of chondroitin sulfate (CS-GAG) from the chondroitin sulfate proteoglycan (CSPG) core protein. Chondroitinase ABC facilitates reinnervation by degrading CS-GAGs around motoneurons. Chondroitinase ABC has the potential for the research of spinal injury .
    Chondroitinase ABC
  • HY-167983
    Cx43 HC-IN-1

    		Gap Junction Protein Neurological Disease
    Cx43 HC-IN-1 (Compound D4) is a selective and orally active inhibitor of connexin hemichannels (Cx43 HC). Cx43 HC-IN-1 effectively inhibits the hemichannel activity mediated by Cx43/Cx45 in denervated skeletal muscle fibers, significantly increasing the reinnervation rate of muscle fibers by neurons. Cx43 HC-IN-1 reduces neuroinflammation and neuronal overexcitation by inhibiting hemichannels in glial cells in the brain, and alleviates epilepsy in mice. Cx43 HC-IN-1 can be used for research on epilepsy and muscle diseases .
    Cx43 HC-IN-1

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