8 Results for "

Resolvin D1

" in MedChemExpress (MCE) Product Catalog:
Products (8)

8 Results for "Resolvin D1" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-125527
CAS No.: 872993-05-0
Purity:  ≥99.0%
Synonyms: RvD1
Resolvin D1 (RvD1), an endogenous pro-resolving mediator of inflammation, is derived from omega-3 docosahexaenoic acid during the resolution phase of acute inflammation. Resolvin D1 blocks proinflammatory neutrophil migration by regulating actin polymerization, reduces TNF-α–mediated inflammation in macrophages, and enhances phagocytosis of apoptotic cells by macrophages .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-125527A
CAS No.: 528583-91-7
Purity:  99.1%
Synonyms: 17(R)-RvD1; AT-RvD1
Target:  

TRP Channel

Research Areas:  

Inflammation/Immunology

17R-Resolvin D1 (17R-RvD1; AT-RvD1) is an aspirin-triggered epimer of Resolvin D1, which exhibits anti-inflammatory activity in mice and human PMNs cells . 17R-Resolvin D1 specificially inhibits TRPV3 with an IC50 of 398 nM and exhibits peripheral anti-nociceptive efficacy .
loading...
    loading...
Cat. No.: HY-125527S
CAS No.: 1881277-32-2
Purity:  99.2%
Synonyms: RvD1-d5
Resolvin D1-d5 is the deuterium labeled Resolvin D1. Resolvin D1 (RvD1), an endogenous pro-resolving mediator of inflammation, is derived from omega-3 docosahexaenoic acid during the resolution phase of acute inflammation. Resolvin D1 blocks proinflammatory neutrophil migration by regulating actin polymerization, reduces TNF-α-mediated inflammation in macrophages, and enhances phagocytosis of apoptotic cells by macrophages .
loading...
    loading...
Cat. No.: HY-128031
CAS No.: 937738-63-1
Synonyms: RvD1 methyl ester
Target:  

Drug Derivative

Research Areas:  

Metabolic Disease

Resolvin D1 methyl ester (RvD1 methyl ester) is the methyl ester of Resolvin D1 (HY-125527). Resolvin D1 methyl ester reduces triglyceride levels .
loading...
    loading...
Cat. No.: HY-172750
Synonyms: 17(R,S)-Benzo-RvD1
Target:  

Drug Derivative

Research Areas:  

Inflammation/Immunology

17(R,S)-Benzo-resolvin D1 (17(R,S)-Benzo-RvD1) is a Resolvin D1 (HY-125527) analogue with pro-resolving and anti-migratory activity. 17(R,S)-Benzo-resolvin D1 attenuates neointimal hyperplasia in a rat model of acute vascular injury .
loading...
    loading...
Cat. No.: HY-145474
CAS No.: 937738-64-2
Target:  

Endogenous Metabolite

Research Areas:  

Inflammation/Immunology

17(R)-Resolvin D1 methyl ester is the methyl ester of Resolvin D1 (RvD1) (HY-125527) induced by Aspirin (HY-14654) with the 17R epimer (AT-RvD1). RvD is a regulator of transendothelial migration of human polymorphonuclear leukocytes and an anti-inflammatory agent. The 17R-trihydroxy-4Z of RvD1 also blocks transendothelial migration of human neutrophils (EC50 approximately 30 nM). AT-RvD1 is an effective form that protects against the rapid inactivation of Resolvin D1 .
loading...
    loading...
Cat. No.: HY-125527AS
Synonyms: 17(R)-RvD1-d5; AT-RvD1-d5
17(R)-Resolvin D1-d5 (17(R)-RvD1-d5) is deuterium labeled 17(R)-Resolvin D1. 17R-Resolvin D1 (17R-RvD1; AT-RvD1) is an aspirin-triggered epimer of Resolvin D1, which exhibits anti-inflammatory activity in mice and human PMNs cells . 17R-Resolvin D1 specificially inhibits TRPV3 with an IC50 of 398 nM and exhibits peripheral anti-nociceptive efficacy .
loading...
    loading...
Cat. No.: HY-125020
CAS No.: 862811-76-5
Target:  

Arrestin

Research Areas:  

Inflammation/Immunology

NCGC00135472 is a potent agonist of resolvin D1 receptor (DRV1), with the EC50 of 0.37 nM and 0.05 μM for β-arrestin and cAMP activities, respectively .
loading...
    loading...