2 Results for "

S1360

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "S1360" in MCE Product Catalog:

25
25 Cited Publications
Cat. No.: HY-12036
CAS No.: 958852-01-2
Purity:  98.28%
Target:  

PI3K mTOR Apoptosis

Research Areas:  

Cancer

GSK1059615 is a dual inhibitor of PI3Kα/β/δ/γ (reversible) and mTOR with IC50 of 0.4 nM/0.6 nM/2 nM/5 nM and 12 nM, respectively.
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Cat. No.: HY-12108
CAS No.: 280571-30-4
Target:  

HIV Integrase HIV

Research Areas:  

Infection

S 1360 is a potent and selective inhibitor of HIV-1 integrase. S 1360 inhibits the catalytic activity of purified integrase ( IC50: 20 nM). The EC50, and CC50 of S 1360 in MTT assay (MT-4 cells infected with HIV-1 IIIB) are 200 nM and 12 μM, respectively. S 1360 has antiviral activity against both X4 tropic and R5 tropic strains, as well as NRTI, NNRTI and PI drug-resistant variants .
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