958852-01-2
958852-01-2
Chemical Structure
GSK1059615
- CAS No.: 958852-01-2
- Formula:C18H11N3O2S
- Molecular Weight:333.36
IUPAC Name: (Z)-5-((4-(pyridin-4-yl)quinolin-6-yl)methylene)thiazolidine-2,4-dione
InChIKey: QDITZBLZQQZVEE-YBEGLDIGSA-N
SMILES: O=C(S/C1=C\C2=CC=C3N=CC=C(C3=C2)C4=CC=NC=C4)NC1=O
Biological Activity: GSK1059615 is a dual inhibitor of PI3Kα/β/δ/γ (reversible) and mTOR with IC50 of 0.4 nM/0.6 nM/2 nM/5 nM and 12 nM, respectively.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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GSK1059615 | 98.81% | GSK1059615 is a dual inhibitor of PI3Kα/β/δ/γ (reversible) and mTOR with IC50 of 0.4 nM/0.6 nM/2 nM/5 nM and 12 nM, respectively. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.62
HY-10109RAS-605240 (Standard) -
Similarity Score 0.53
HY-12529Ro-3306 -
Similarity Score 0.53
HY-11619815-PGDH-IN-2 -
Similarity Score 0.52
HY-131049Antimicrobial agent-30 -
Similarity Score 0.52
HY-W412264Pim-1/2 kinase inhibitor 1 -
Similarity Score 0.52
HY-48869PI3K-IN-46 -
Similarity Score 0.51
HY-13530CAY10505 -
Similarity Score 0.51
HY-165161POSH-IN-1 -
Similarity Score 0.51
HY-118521AS-041164 -
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