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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
10 Results for "
SREBF1
" in MedChemExpress (MCE) Product Catalog:
Products (10)
10 Results for "SREBF1" in MCE Product Catalog:
2
2 Cited Publications
製品番号: HY-50670
CAS 番号: 942999-61-3
研究分野:
DGAT-1 inhibitor 2 is an orally active DGAT-1 inhibitor with IC50 values of 15 nM and 9 nM for human DGAT-1 and rat DGAT-1, respectively. DGAT-1 inhibitor 2 increases ROS concentration, GRP78, and PERK protein abundance. DGAT-1 inhibitor 2 increases SREBF1, CPT1A, and MTTP mRNA in fatty acid-treated cells. DGAT-1 inhibitor 2 improves obesity [1] .
2
1
1 Cited Publications
製品番号: HY-P1856
CAS 番号: 33017-11-7
Target:
製品番号: HY-RS13757
Target:
研究分野:
SREBF1 Human Pre-designed siRNA Set A contains three designed siRNAs for SREBF1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
製品番号: HY-RS29460
Target:
研究分野:
SREBF1 Pig Pre-designed siRNA Set A contains three designed siRNAs for SREBF1 (Pig), as well as a negative control, a positive control, and a FAM-labeled negative control.
製品番号: HY-RS17721
Target:
研究分野:
Srebf1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Srebf1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
製品番号: HY-RS24186
Target:
研究分野:
Srebf1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Srebf1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
製品番号: HY-50670R
CAS 番号: 942999-61-3
Target:
Carnitine Palmitoyltransferase (CPT) Reference Standards Acyltransferase Reactive Oxygen Species (ROS) HSP PERK
研究分野:
DGAT-1 inhibitor 2 (Standard) is the analytical standard of DGAT-1 inhibitor 2 (HY-50670). This product is intended for research and analytical applications. DGAT-1 inhibitor 2 is an orally active DGAT-1 inhibitor with IC50 values of 15 nM and 9 nM for human DGAT-1 and rat DGAT-1, respectively. DGAT-1 inhibitor 2 increases ROS concentration, GRP78, and PERK protein abundance. DGAT-1 inhibitor 2 increases SREBF1, CPT1A, and MTTP mRNA in fatty acid-treated cells. DGAT-1 inhibitor 2 improves obesity [1] .
製品番号: HY-184415
研究分野:
Syk/HDAC6-IN-1 is a dual SYK/HDAC6 selective inhibitor with IC50 values of 0.19 nM (SYK) and 0.66 nM (HDAC6). Syk/HDAC6-IN-1 downregulates p-SYK to block downstream AKT/FOXO1 signaling, elevates acetylated histone H3 and α-tubulin via HDAC suppression, represses SREBF1 -mediated lipid biosynthetic pathways, triggers G0/G1 cell cycle arrest and robust mitochondrial-dependent caspase-3-mediated apoptosis in leukemia cells. Syk/HDAC6-IN-1 can be used for the research of FLT3-mutant acute myeloid leukemia [1].
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
