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Results for "

SSAT

" in MedChemExpress (MCE) Product Catalog:

8

Inhibitors & Agonists

2

Antibodies

3

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-13610A
    N1,N11-Diethylnorspermine tetrahydrochloride
    4 Publications Verification

    Diethylnorspermine tetrahydrochloride; DENSPM tetrahydrochloride; BENSPM tetrahydrochloride

    		 Caspase mTOR Cancer
    N1, N11-Diethylnorspermine tetrahydrochloride (DENSPM tetrahydrochloride) is a potent anticancer agent. N1,N11-Diethylnorspermine tetrahydrochloride activates polyamine catabolism and downregulates mTOR protein. N1,N11-Diethylnorspermine tetrahydrochloride induces the release of cytochrome c from mitochondria, resulting in activation of caspase 3. N1,N11-Diethylnorspermine tetrahydrochloride kills glioblastoma multiforme (GBM) through induction of SSAT (spermidine/spermine N1-acetyltransferase) coupled with H2O2 production .
    N1,N11-Diethylnorspermine tetrahydrochloride
  • HY-B1787
    Sulindac sulfone

    		mTOR Drug Metabolite CDK PPAR Apoptosis Cancer
    Sulindac sulfone is an orally active metabolite of Sulindac (HY-B0008). Sulindac sulfone activates PPARγ and drives transcriptional induction of SSAT by binding to the PPRE-2 element. Sulindac sulfone induces Apoptosis. Sulindac sulfone negatively regulates the function of VDAC1/2 to inhibit the mTORC1 pathway, reduces Cyclin D1 levels, and induces G1 cell cycle arrest in colon cancer cells. Sulindac sulfone exerts colon cancer preventive effects through a COX-independent mechanism. Sulindac sulfone can be used in research related to colon cancer .
    Sulindac sulfone
  • HY-13610B
    N1,N11-Diethylnorspermine hydrobromide

    		Caspase Cancer
    N1,N11-Diethylnorspermine hydrobromide is a potent anticancer agent. N1,N11-Diethylnorspermine hydrobromide is a spermine analog that activates polyamine catabolism. N1,N11-Diethylnorspermine hydrobromide induces the release of cytochrome c from mitochondria, resulting in activation of caspase 3. N1,N11-Diethylnorspermine hydrobromide kills glioblastoma multiforme (GBM) cells through induction of SSAT (spermidine/spermine N1-acetyltransferase) coupled with H2O2 production .
    N1,N11-Diethylnorspermine hydrobromide
  • HY-13610
    N1,N11-Diethylnorspermine

    Diethylnorspermine; BENSPM; DENSPM; BE-333

    		 Caspase mTOR Cancer
    N1,N11-Diethylnorspermine is a synthetic analog of the naturally occurring polyamine spermine, can induce polyamine depletion and inhibit tumor cell growth. N1,N11-Diethylnorspermine activates polyamine catabolism and downregulates mTOR protein. N1,N11-Diethylnorspermine induces the release of cytochrome c from mitochondria, resulting in activation of caspase 3. N1,N11-Diethylnorspermine tetrahydrochloride kills glioblastoma multiforme (GBM) through induction of SSAT (spermidine/spermine N1-acetyltransferase) coupled with H2O2 production .
    N1,N11-Diethylnorspermine
  • HY-RS12455
    SAT1 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    SAT1 Human Pre-designed siRNA Set A contains three designed siRNAs for SAT1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    SAT1 Human Pre-designed siRNA Set A
    SAT1 Human Pre-designed siRNA Set A
  • HY-13610AR
    N1,N11-Diethylnorspermine tetrahydrochloride (Standard)

    Diethylnorspermine tetrahydrochloride (Standard); DENSPM tetrahydrochloride (Standard); BENSPM tetrahydrochloride (Standard)

    		 Caspase mTOR Reference Standards Cancer
    N1,N11-Diethylnorspermine (tetrahydrochloride) (Standard) is the analytical standard of N1,N11-Diethylnorspermine (tetrahydrochloride). This product is intended for research and analytical applications. N1, N11-Diethylnorspermine tetrahydrochloride (DENSPM tetrahydrochloride) is a potent anticancer agent. N1,N11-Diethylnorspermine tetrahydrochloride activates polyamine catabolism and downregulates mTOR protein. N1,N11-Diethylnorspermine tetrahydrochloride induces the release of cytochrome c from mitochondria, resulting in activation of caspase 3. N1,N11-Diethylnorspermine tetrahydrochloride kills glioblastoma multiforme (GBM) through induction of SSAT (spermidine/spermine N1-acetyltransferase) coupled with H2O2 production .
    N1,N11-Diethylnorspermine tetrahydrochloride (Standard)
  • HY-RS17374
    Sat1 Mouse Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Sat1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Sat1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Sat1 Mouse Pre-designed siRNA Set A
    Sat1 Mouse Pre-designed siRNA Set A
  • HY-RS23828
    Sat1 Rat Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Sat1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Sat1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Sat1 Rat Pre-designed siRNA Set A
    Sat1 Rat Pre-designed siRNA Set A

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