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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
6 Results for "
Sec61α
" in MedChemExpress (MCE) Product Catalog:
Products (6)
6 Results for "Sec61α" in MCE Product Catalog:
Cat. No.: HY-182690
CAS No.: 1883356-12-4
CK147 is a Sec61α translocase inhibitor that blocks the co-translational translocation of proteins by binding to and inhibiting the Sec61 protein translocation channel on the endoplasmic reticulum membrane. CK147 exhibits potent CD4 downregulation activity with an IC50 of 0.04 µM. CK147 prevents HIV entry into host cells and shows significant cytotoxicity. CK147 can be used in studies related to HIV infection .
Cat. No.: HY-P87069
Synonyms: chunp6898 antibody; fb62c11 antibody; HSec61 antibody; protein transport protein Sec61 alpha subunit antibody; protein transport protein Sec61 subunit alpha antibody; Protein transport protein Sec61 subunit alpha isoform 1 antibody; S61A1_HUMAN antibody; Sec 61 antibody; Sec 61A antibody; Sec61 alpha 1 antibody; chunp6898 antibody; fb62c11 antibody; HSec61 antibody; protein transport protein Sec61 alpha subunit antibody; protein transport protein Sec61 subunit alpha antibody; Protein transport protein Sec61 subunit alpha isoform 1 antibody; S61A1_HUMAN antibody; Sec 61 antibody; Sec 61A antibody; Sec61 alpha 1 antibody; Sec61 alpha 1 subunit antibody; Sec61 alpha 1 subunit (S. cerevisiae) antibody; Sec61 alpha-1 antibody; Sec61 antibody; Sec61 homolog antibody; Sec61A1 antibody; Sec61aa antibody;
Cat. No.: HY-182674
CAS No.: 1322645-32-8
Target:
VGD020 is a highly potent and selective Sec61 translocon inhibitor . VGD020 suppresses the expression of cell surface CD4 by inhibiting signal peptide-dependent co-translational ER translocation, interferes with the initiation of ER translocation of dengue virus polyprotein, and reduces the expression of Sortilin in breast cancer cells. VGD020 exhibits broad anti-flavivirus and anti-HIV activities. VGD020 can be used in research related to dengue virus infection, Zika virus infection, yellow fever virus infection, human immunodeficiency virus infection, and breast cancer .
Cat. No.: HY-P10466
CAS No.: 2377734-91-1
Research Areas:
Cat. No.: HY-P10466A
Research Areas:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
