7 Results for "

Spinosae

" in MedChemExpress (MCE) Product Catalog:
Products (7)

7 Results for "Spinosae" in MCE Product Catalog:

4
Jujuboside A
Jujuboside A
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4 Cited Publications
Cat. No.: HY-N0659
CAS No.: 55466-04-1
Category:  

Triterpenes Terpenoids Plants Actaea dahurica Turcz. ex Fisch. & C. A. Mey. Rhamnaceae

Target:  

GABA Receptor

Jujuboside A is a glycoside extracted from Semen Ziziphi Spinosae, a Chinese herbal medicine used to treat insomnia and anxiety.
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Jujuboside B
Jujuboside B
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Cat. No.: HY-N0660
CAS No.: 55466-05-2
Category:  

Cardiovascular Disease Triterpenes other families Terpenoids Plants Disease Research Fields

Target:  

Apoptosis PARP Caspase AMPK Autophagy VEGFR Keap1-Nrf2 STING 11β-HSD Ferroptosis PI3K Akt p38 MAPK ERK

Jujuboside B is a bioactive saponin component isolated from Ziziphi Spinosae Semen (sour jujube seed), with oral efficacy and blood-brain barrier permeability. Jujuboside B induces acute leukemia cell death and drives necroptosis apoptosis by activating the RIPK1/RIPK3/MLKL pathway. Jujuboside B upregulates the expression of NOXA, PARP and caspase-3, activates AMPK, inhibits the proliferation of breast cancer cells, and induces cell apoptosis and autophagy. Jujuboside B inhibits angiogenesis and tumor growth by blocking the VEGFR-2 signaling pathway. Jujuboside B alleviates liver injury in mice by regulating the Nrf2-STING signaling pathway . Jujuboside B alleviates liver injury by regulating anti-inflammatory responses and downregulating the expression of 11β-HSD2. Jujuboside B induces ferroptosis and overcomes radioresistance in non-small cell lung cancer via the PPARγ-ATF3-Gpx4 signaling pathway. Jujuboside B exerts inhibitory effects on platelet aggregation. Jujuboside B inhibits febrile seizures by suppressing the activity of AMPA receptors. Jujuboside B reverses chronic unpredictable mild stress-promoted tumor progression by blocking the PI3K/Akt and MAPK/ERK pathways and dephosphorylating CREB signaling. Jujuboside B is applicable to related studies on acute leukemia, breast cancer, PM2.5-induced lung injury, hepatotoxicity, liver injury, colorectal cancer, non-small cell lung cancer, thromboembolic diseases, cardiovascular diseases associated with high platelet aggregation, febrile seizures, and depressive-like phenotypes .
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DL-O-Phosphoserine (Standard)
DL-O-Phosphoserine (Standard)
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Cat. No.: HY-15130R
CAS No.: 17885-08-4
Category:  

Microorganisms Ketones, Aldehydes, Acids Endogenous metabolite

Target:  

Reference Standards Endogenous Metabolite

Jujuboside A (Standard) is the analytical standard of Jujuboside A. This product is intended for research and analytical applications. Jujuboside A is a glycoside extracted from Semen Ziziphi Spinosae, a Chinese herbal medicine used to treat insomnia and anxiety.
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Jujuboside B1
Jujuboside B1
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Cat. No.: HY-N2047
CAS No.: 68144-21-8
Category:  

Triterpenes other families Terpenoids Other Diseases Plants Disease Research Fields

Target:  

Others

Jujuboside B1, a dammarane-type triterpene oligoglycoside, is isolated from Ziziphi Spinosae Semen .
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Jujuboside A (Standard)
Jujuboside A (Standard)
0 Images
Cat. No.: HY-N0659R
CAS No.: 55466-04-1
Category:  

Triterpenes Terpenoids Plants Actaea dahurica Turcz. ex Fisch. & C. A. Mey. Rhamnaceae

Target:  

Reference Standards GABA Receptor

Jujuboside A (Standard) is the analytical standard of Jujuboside A. This product is intended for research and analytical applications. Jujuboside A is a glycoside extracted from Semen Ziziphi Spinosae, a Chinese herbal medicine used to treat insomnia and anxiety.
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Semen ziziphi spinosae extract
Semen ziziphi spinosae extract
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Cat. No.: HY-N19048
Category:  

Extract

Target:  

Others

Semen Ziziphi Spinosae Extract is derived from the dried seeds of Ziziphus jujuba Mill.var.spinosa, a plant of the Rhamnaceae family. The active ingredients include flavonoid glycosides, triterpenes, saponins and organic acids, etc.
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Jujuboside B (Standard)
Jujuboside B (Standard)
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Cat. No.: HY-N0660R
CAS No.: 55466-05-2
Category:  

Triterpenes other families Terpenoids Plants

Target:  

Reference Standards ERK p38 MAPK Akt PI3K 11β-HSD STING VEGFR Ferroptosis Autophagy Apoptosis Keap1-Nrf2 Caspase PARP AMPK

Jujuboside B (Standard) is the analytical standard of Jujuboside B. This product is intended for research and analytical applications. Jujuboside B is a bioactive saponin component isolated from Ziziphi Spinosae Semen (sour jujube seed), with oral efficacy and blood-brain barrier permeability. Jujuboside B induces acute leukemia cell death and drives necroptosis apoptosis by activating the RIPK1/RIPK3/MLKL pathway. Jujuboside B upregulates the expression of NOXA, PARP and caspase-3, activates AMPK, inhibits the proliferation of breast cancer cells, and induces cell apoptosis and autophagy. Jujuboside B inhibits angiogenesis and tumor growth by blocking the VEGFR-2 signaling pathway. Jujuboside B alleviates liver injury in mice by regulating the Nrf2-STING signaling pathway . Jujuboside B alleviates liver injury by regulating anti-inflammatory responses and downregulating the expression of 11β-HSD2. Jujuboside B induces ferroptosis and overcomes radioresistance in non-small cell lung cancer via the PPARγ-ATF3-Gpx4 signaling pathway. Jujuboside B exerts inhibitory effects on platelet aggregation. Jujuboside B inhibits febrile seizures by suppressing the activity of AMPA receptors. Jujuboside B reverses chronic unpredictable mild stress-promoted tumor progression by blocking the PI3K/Akt and MAPK/ERK pathways and dephosphorylating CREB signaling. Jujuboside B is applicable to related studies on acute leukemia, breast cancer, PM2.5-induced lung injury, hepatotoxicity, liver injury, colorectal cancer, non-small cell lung cancer, thromboembolic diseases, cardiovascular diseases associated with high platelet aggregation, febrile seizures, and depressive-like phenotypes.
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