17885-08-4
Chemical Structure
DL-O-Phosphoserine
- CAS No.: 17885-08-4
- Formula:C3H8NO6P
- Molecular Weight:185.07
IUPAC Name: O-phosphonoserine
InChIKey: BZQFBWGGLXLEPQ-UHFFFAOYSA-N
SMILES: OP(OCC(C(O)=O)N)(O)=O
Biological Activity: DL-O-Phosphoserine is a normal metabolite in human biofluids and is a mixture of phosphoserine with two stereochemical structures (D-type and L-type O-phospho-serine). O-phospho-L-serine is a competitive inhibitor of serine racemase and phagocytosis. O-phospho-L-serine inhibits the enzymatic reaction by competing with the active site of serine racemase, thereby affecting the production of D-serine. O-phospho-L-serine also mimics the phosphatidylserine head group, binds to the phosphatidylserine receptor, interferes with phagocytic signal transduction, and partially blocks the phagocytosis of apoptotic cells by cells. O-phospho-L-serin can be used in the research of retinal regeneration, bone repair, and insect growth and development[1][2].
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DL-O-Phosphoserine | 98.0% | DL-O-Phosphoserine is a normal metabolite in human biofluids and is a mixture of phosphoserine with two stereochemical structures (D-type and L-type O-phospho-serine). O-phospho-L-serine is a competitive inhibitor of serine racemase and phagocytosis. O-phospho-L-serine inhibits the enzymatic reaction by competing with the active site of serine racemase, thereby affecting the production of D-serine. O-phospho-L-serine also mimics the phosphatidylserine head group, binds to the phosphatidylserine receptor, interferes with phagocytic signal transduction, and partially blocks the phagocytosis of apoptotic cells by cells. O-phospho-L-serin can be used in the research of retinal regeneration, bone repair, and insect growth and development. | ||||||||||||||||||||
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DL-O-Phosphoserine (Standard) | 99.86% | Jujuboside A (Standard) is the analytical standard of Jujuboside A. This product is intended for research and analytical applications. Jujuboside A is a glycoside extracted from Semen Ziziphi Spinosae, a Chinese herbal medicine used to treat insomnia and anxiety. | ||||||||||||||||||||
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- [1]. Bailey TJ, et al. The inhibitor of phagocytosis, O-phospho-L-serine, suppresses Müller glia proliferation and cone cell regeneration in the light-damaged zebrafish retina. Exp Eye Res. 2010 Nov;91(5):601-12. [Content Brief]
- [2]. Mai R, Lux R, Proff P, Lauer G, Pradel W, Leonhardt H, Reinstorf A, Gelinsky M, Jung R, Eckelt U, Gedrange T, Stadlinger B. O-phospho-L-serine: a modulator of bone healing in calcium-phosphate cements. Biomed Tech (Berl). 2008 Oct;53(5):229-33. [Content Brief]
