22 Results for "

TEMPO

" in MedChemExpress (MCE) Product Catalog:
Products (22)

22 Results for "TEMPO" in MCE Product Catalog:

168
Mito-TEMPO
Mito-TEMPO
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168 Publications Verification
Cat. No.: HY-112879
CAS No.: 1334850-99-5
Purity:  99.19%
Target:  

Calcium Channel PINK1/Parkin Mitochondrial Metabolism Apoptosis Autophagy NOD-like Receptor (NLR)

Research Areas:  

Cardiovascular Disease Neurological Disease Metabolic Disease Inflammation/Immunology

Mito-TEMPO is a mitochondria-targeted antioxidant. Mito-TEMPO induces mitophagy by activating the PINK1/Parkin pathway, inhibits NLRP3 inflammasome activation, restores mitochondrial membrane potential, and improves renal function and podocyte injury. Mito-TEMPO regulates Ca 2+ homeostasis, inhibits Bnip3 overexpression, shortens action potential duration, and exerts antiarrhythmic effects. Mito-TEMPO reverses premature senescence, reduces trabecular bone loss, and decreases cell apoptosis. Mito-TEMPO can be used in studies of chronic kidney disease, age-related cardiac dysfunction, postmenopausal osteoporosis, and ischemic stroke .
28
Tempol
Tempol
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28 Cited Publications
Cat. No.: HY-100561
CAS No.: 2226-96-2
Purity:  99.73%
Synonyms: 4-Hydroxy-TEMPO
Target:  

Reactive Oxygen Species (ROS) Autophagy

Research Areas:  

Cancer

Tempol is a general superoxide dismutase (SOD)-mimetic agent that efficiently neutralizes reactive oxygen species (ROS).
13
Tempo
Tempo
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13 Cited Publications
Cat. No.: HY-W001187
CAS No.: 2564-83-2
Target:  

Mitochondrial Metabolism DNA/RNA Synthesis Reactive Oxygen Species (ROS)

Research Areas:  

Cancer

Tempo is a nitric oxide radical and a selective scavenger of ROS in mitochondria. Tempo is also an organocatalyst that disproportionates superoxide and oxidizes primary alcohols to aldehydes in a catalytic cycle. Tempo has mutagenic and antioxidant effects and can induceDNA strand breaks. Tempo also exerts cytotoxic and mutagenic properties in mouse lymphoma cells .
2
N3-TEMPO
N3-TEMPO
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2 Cited Publications
Cat. No.: HY-151847
CAS No.: 63697-61-0
Purity:  99.41%
Target:  

ADC Linkers

Research Areas:  

Others

N3-TEMPO is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
4-Amino-TEMPO
4-Amino-TEMPO
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Cat. No.: HY-W002004
CAS No.: 14691-88-4
Synonyms: 4-Amino-2,2,6,6-tetramethylpiperidine-1-oxyl
4-Amino-TEMPO (4-Amino-2,2,6,6-tetramethylpiperidine-1-oxyl) is a stable nitroxide radical and N-nucleophile based on TEMPO. 4-Amino-TEMPO has superoxide dismutase-mimetic activity, can protect cells from oxidative damage, and has radioprotective effects. 4-Amino-TEMPO is widely used in fields such as biomedicine, materials science, and industrial production. 4-Amino-TEMPO can be used as a spin label to detect free radicals, an oxidation catalyst in industrial production, and an antioxidant stabilizer for polymers, among others .
Tempone
Tempone
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Cat. No.: HY-129242
CAS No.: 2896-70-0
Purity:  97.01%
Synonyms: 4-Oxo-TEMPO
Target:  

SOD

Research Areas:  

Others

Tempone (4-Oxo-Tempo) is a stable water-soluble nitro radical. Tempone is widely used as a contrast agent for metabolic activity and hypoxic sensitivity in electron spin resonance spectroscopy, magnetic resonance imaging and dynamic nuclear polarization. Tempone reduces superoxide radicals by mimicking the activity of superoxide dismutase (SOD), thereby reducing the formation of hydroxyl radicals and peroxynitrites. Tempone can be used in the study of ischemia-reperfusion injury and acute renal failure .
Tempo-d18
Tempo-d18
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Cat. No.: HY-W001187S
CAS No.: 205679-68-1
Tempo-d18 is the deuterium labeled Tempo . Tempo is a classic nitroxide radical and is a selective scavenger of ROS that dismutases superoxide in the catalytic cycle. Tempo induces DNA-strand breakage. Tempo can be used as an organocatalyst for the oxidation of primary alcohols to aldehydes. Tempo has mutagenic and antioxidant effects .
Tempone-15N,d16
Tempone-15N,d16
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Cat. No.: HY-129242S
CAS No.: 80404-14-4
Synonyms: 4-Oxo-TEMPO-15N,d16
Tempone- 15N,d16 is the deuterium and 15N labeled Tempone .
Tempo (Standard)
Tempo (Standard)
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Cat. No.: HY-W001187R
CAS No.: 2564-83-2
Target:  

Mitochondrial Metabolism DNA/RNA Synthesis Reactive Oxygen Species (ROS) Reference Standards

Research Areas:  

Cancer

Tempo (Standard) is the analytical standard of Tempo. This product is intended for research and analytical applications. Tempo is a nitric oxide radical and a selective scavenger of ROS in mitochondria. Tempo is also an organocatalyst that disproportionates superoxide and oxidizes primary alcohols to aldehydes in a catalytic cycle. Tempo has mutagenic and antioxidant effects and can induceDNA strand breaks. Tempo also exerts cytotoxic and mutagenic properties in mouse lymphoma cells [4].
Tempol-d17,15N
Tempol-d17,15N
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Cat. No.: HY-100561S
CAS No.: 90429-66-6
Synonyms: 4-Hydroxy-TEMPO-d17,15N
Tempol-d17, 15N is the deuterium labeled Tempol . Tempol is a general superoxide dismutase (SOD)-mimetic agent that efficiently neutralizes reactive oxygen species (ROS) .
Acid-PEG5-TEMPO
Acid-PEG5-TEMPO
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Cat. No.: HY-140512
CAS No.: 2055040-79-2
Target:  

PROTAC Linkers

Research Areas:  

Cancer

Acid-PEG5-TEMPO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
4-Amino-TEMPO-d17
4-Amino-TEMPO-d17
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Cat. No.: HY-W002004S1
CAS No.: 70588-04-4
Synonyms: 4-Amino-2,2,6,6-tetramethylpiperidine-1-oxyl-d17
4-Amino-TEMPO-d17 (4-Amino-2,2,6,6-tetramethylpiperidine-1-oxyl-d17) is the deuterium labeled 4-Amino-TEMPO (HY-W002004). 4-Amino-TEMPO (4-Amino-2,2,6,6-tetramethylpiperidine-1-oxyl) is a stable nitroxide radical and N-nucleophile based on TEMPO. 4-Amino-TEMPO has superoxide dismutase-mimetic activity, can protect cells from oxidative damage, and has radioprotective effects. 4-Amino-TEMPO is widely used in fields such as biomedicine, materials science, and industrial production. 4-Amino-TEMPO can be used as a spin label to detect free radicals, an oxidation catalyst in industrial production, and an antioxidant stabilizer for polymers, among others .
Tempol (Standard)
Tempol (Standard)
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Cat. No.: HY-100561R
CAS No.: 2226-96-2
Synonyms: 4-Hydroxy-TEMPO (Standard)
Target:  

Reference Standards Reactive Oxygen Species (ROS) Autophagy

Research Areas:  

Cancer

Tempol (Standard) is the analytical standard of Tempol. This product is intended for research and analytical applications. Tempol is a general superoxide dismutase (SOD)-mimetic agent that efficiently neutralizes reactive oxygen species (ROS).
4-Isocyanato-TEMPO,Technical grade
4-Isocyanato-TEMPO,Technical grade
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Cat. No.: HY-W777072
CAS No.: 88418-69-3
Target:  

HIV

Research Areas:  

Others

4-isocyanato TEMPO is a spin labeling reagent used to label the 2’-position in RNA. It has been used to study HIV-1 transactivation response RNA and hammerhead ribosome dynamics by electron paramagnetic resonance (EPR) spectroscopy.
4-Amino-TEMPO-d17,15N
4-Amino-TEMPO-d17,15N
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Cat. No.: HY-W002004S
CAS No.: 97461-87-5
Synonyms: 4-Amino-2,2,6,6-tetramethylpiperidine-1-oxyl-d17,15N
4-Amino-TEMPO-d17, 15N (4-Amino-2,2,6,6-tetramethylpiperidine-1-oxyl-d17, 15N) is the deuterium labeled 4-Amino-TEMPO-d17 (HY-W002004S1). 4-Amino-TEMPO (4-Amino-2,2,6,6-tetramethylpiperidine-1-oxyl) is a stable nitroxide radical and N-nucleophile based on TEMPO. 4-Amino-TEMPO has superoxide dismutase-mimetic activity, can protect cells from oxidative damage, and has radioprotective effects. 4-Amino-TEMPO is widely used in fields such as biomedicine, materials science, and industrial production. 4-Amino-TEMPO can be used as a spin label to detect free radicals, an oxidation catalyst in industrial production, and an antioxidant stabilizer for polymers, among others .
Tempol-d17
Tempol-d17
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Cat. No.: HY-100561S1
CAS No.: 100326-46-3
Synonyms: 4-Hydroxy-TEMPO-d17
Tempol-d17 is the deuterium labeled Tempol . Tempol is a general superoxide dismutase (SOD)-mimetic agent that efficiently neutralizes reactive oxygen species (ROS) .
Tempone-d16
Tempone-d16
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Cat. No.: HY-129242S1
CAS No.: 36763-53-8
Synonyms: 4-Oxo-TEMPO-d16
Tempone-d16 is the deuterium labeled Tempone .
16:0 Tempo PC
16:0 Tempo PC
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Cat. No.: HY-179762
CAS No.: 63658-52-6
Target:  

Others

Research Areas:  

Others

16:0 Tempo PC is a phosphocholine with a TEMPO group. (2,2,6,6-tetramethylpiperidin-1-yl)oxyl (TEMPO) is commonly used as a spin-label for lipid membrane studies. TEMPO alwayss acts as a spin probe are in electron resonance spectroscopy, as a paramagnetic contrast agent in NMR, and as oxygen-sensitive probes in biological systems.
4-Palmitamido-TEMPO
4-Palmitamido-TEMPO
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Cat. No.: HY-W705452
CAS No.: 22977-65-7
Target:  

Others

Research Areas:  

Metabolic Disease

4-Palmitamido-TEMPO is an aliphatic derivative of TEMPO. It is incorporated into vesicles and cell membranes and has been used to study the entrapment of molecules in phosphatidylcholine vesicles.
4-Phosphonooxy-tempo
4-Phosphonooxy-tempo
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Cat. No.: HY-179316
CAS No.: 22690-04-6
Target:  

Biochemical Assay Reagents

Research Areas:  

Others

4-Phosphonooxy-tempo is an anionic nitroxide spin probe. 4-Phosphonooxy-tempo can be transported by a band 3 protein to permeate the membrane and then react with reductants contained in cytosol. 4-Phosphonooxy-tempo can be used as biomembrane anion channel functional probe .
Assay Types