70588-04-4
Chemical Structure
4-Amino-TEMPO-d17
Synonym(s): 4-Amino-2,2,6,6-tetramethylpiperidine-1-oxyl-d17
- CAS No.: 70588-04-4
- Formula:C9H2D17N2O
- Molecular Weight:188.36
IUPAC Name: 2,2,6,6-tetrakis(methyl-d3)-1-(l1-oxidanyl)piperidin-3,3,4,5,5-d5-4-amine
InChIKey: XUXUHDYTLNCYQQ-DEMDKEALSA-N
SMILES: [O]N1C(C([2H])([2H])[2H])(C([2H])([2H])C(C([2H])([2H])C1(C([2H])([2H])[2H])C([2H])([2H])[2H])([2H])N)C([2H])([2H])[2H]
Biological Activity: 4-Amino-TEMPO-d17 (4-Amino-2,2,6,6-tetramethylpiperidine-1-oxyl-d17) is the deuterium labeled 4-Amino-TEMPO (HY-W002004). 4-Amino-TEMPO (4-Amino-2,2,6,6-tetramethylpiperidine-1-oxyl) is a stable nitroxide radical and N-nucleophile based on TEMPO. 4-Amino-TEMPO has superoxide dismutase-mimetic activity, can protect cells from oxidative damage, and has radioprotective effects. 4-Amino-TEMPO is widely used in fields such as biomedicine, materials science, and industrial production. 4-Amino-TEMPO can be used as a spin label to detect free radicals, an oxidation catalyst in industrial production, and an antioxidant stabilizer for polymers, among others[1][2].
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4-Amino-TEMPO-d17 | 4-Amino-TEMPO-d17 (4-Amino-2,2,6,6-tetramethylpiperidine-1-oxyl-d17) is the deuterium labeled 4-Amino-TEMPO (HY-W002004). 4-Amino-TEMPO (4-Amino-2,2,6,6-tetramethylpiperidine-1-oxyl) is a stable nitroxide radical and N-nucleophile based on TEMPO. 4-Amino-TEMPO has superoxide dismutase-mimetic activity, can protect cells from oxidative damage, and has radioprotective effects. 4-Amino-TEMPO is widely used in fields such as biomedicine, materials science, and industrial production. 4-Amino-TEMPO can be used as a spin label to detect free radicals, an oxidation catalyst in industrial production, and an antioxidant stabilizer for polymers, among others. | |||||||||||||||||||||
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4-Amino-TEMPO-d17,15N | 4-Amino-TEMPO-d17,15N (4-Amino-2,2,6,6-tetramethylpiperidine-1-oxyl-d17,15N) is the deuterium labeled 4-Amino-TEMPO-d17 (HY-W002004S1). 4-Amino-TEMPO (4-Amino-2,2,6,6-tetramethylpiperidine-1-oxyl) is a stable nitroxide radical and N-nucleophile based on TEMPO. 4-Amino-TEMPO has superoxide dismutase-mimetic activity, can protect cells from oxidative damage, and has radioprotective effects. 4-Amino-TEMPO is widely used in fields such as biomedicine, materials science, and industrial production. 4-Amino-TEMPO can be used as a spin label to detect free radicals, an oxidation catalyst in industrial production, and an antioxidant stabilizer for polymers, among others. | |||||||||||||||||||||
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4-Amino-TEMPO | 99.84% | 4-Amino-TEMPO (4-Amino-2,2,6,6-tetramethylpiperidine-1-oxyl) is a stable nitroxide radical and N-nucleophile based on TEMPO. 4-Amino-TEMPO has superoxide dismutase-mimetic activity, can protect cells from oxidative damage, and has radioprotective effects. 4-Amino-TEMPO is widely used in fields such as biomedicine, materials science, and industrial production. 4-Amino-TEMPO can be used as a spin label to detect free radicals, an oxidation catalyst in industrial production, and an antioxidant stabilizer for polymers, among others. | ||||||||||||||||||||
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- [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
- [2]. Gergely M, et al. 4‐Amino‐TEMPO as N‐Nucleophile in Palladium‐Catalyzed Aminocarbonylation. Journal of Heterocyclic Chemistry, 2017, 54(1): 634-640.