100326-46-3
100326-46-3
Chemical Structure
Tempol-d17
Synonym(s): 4-Hydroxy-TEMPO-d17
- CAS No.: 100326-46-3
- Formula:C9HD17NO2
- Molecular Weight:189.35
InChIKey: UZFMOKQJFYMBGY-DEMDKEALSA-N
SMILES: [O]N(C(C([2H])([2H])[2H])(C1([2H])[2H])C([2H])([2H])[2H])C(C([2H])([2H])[2H])(C([2H])([2H])C1([2H])O)C([2H])([2H])[2H]
Biological Activity: Tempol-d17 is the deuterium labeled Tempol[1]. Tempol is a general superoxide dismutase (SOD)-mimetic agent that efficiently neutralizes reactive oxygen species (ROS)[2][3].
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Tempol-d17 | Tempol-d17 is the deuterium labeled Tempol. Tempol is a general superoxide dismutase (SOD)-mimetic agent that efficiently neutralizes reactive oxygen species (ROS). | |||||||||||||||||||||
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Tempol (Standard) | ≥98% | Tempol (Standard) is the analytical standard of Tempol. This product is intended for research and analytical applications. Tempol is a general superoxide dismutase (SOD)-mimetic agent that efficiently neutralizes reactive oxygen species (ROS). | ||||||||||||||||||||
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Tempol-d17,15N | 98.44% | Tempol-d17,15N is the deuterium labeled Tempol. Tempol is a general superoxide dismutase (SOD)-mimetic agent that efficiently neutralizes reactive oxygen species (ROS). | ||||||||||||||||||||
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Tempol | 99.73% | Tempol is a general superoxide dismutase (SOD)-mimetic agent that efficiently neutralizes reactive oxygen species (ROS). | ||||||||||||||||||||
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References
- [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
- [2]. Vilar-Pereira G, et al. Resveratrol Reverses Functional Chagas Heart Disease in Mice. PLoS Pathog. 2016 Oct 27;12(10):e1005947. [Content Brief]
- [3]. Chatterjee PK, et al. Tempol, a membrane-permeable radical scavenger, reduces oxidant stress-mediated renal dysfunction and injury in the rat. Kidney Int. 2000 Aug58(2):658-73. [Content Brief]
