100326-46-3
100326-46-3
Chemical Structure
Tempol-d17
Synonym(s): 4-Hydroxy-TEMPO-d17; MBM-02-d17
- CAS No.: 100326-46-3
- Formula:C9HD17NO2
- Molecular Weight:189.35
IUPAC Name: (S)-5-chloropentan-2-ol
InChIKey: UZFMOKQJFYMBGY-DEMDKEALSA-N
SMILES: [O]N(C(C([2H])([2H])[2H])(C1([2H])[2H])C([2H])([2H])[2H])C(C([2H])([2H])[2H])(C([2H])([2H])C1([2H])O)C([2H])([2H])[2H]
Biological Activity: Tempol-d17 is the deuterium labeled Tempol[1]. Tempol is a general superoxide dismutase (SOD)-mimetic agent that efficiently neutralizes reactive oxygen species (ROS)[2][3].
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Tempol-d17 | Tempol-d17 is the deuterium labeled Tempol. Tempol is a general superoxide dismutase (SOD)-mimetic agent that efficiently neutralizes reactive oxygen species (ROS). | |||||||||||||||||||||
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Tempol (Standard) | ≥98% | Tempol (Standard) is the analytical standard of Tempol. This product is intended for research and analytical applications. Tempol is a general superoxide dismutase (SOD)-mimetic agent that efficiently neutralizes reactive oxygen species (ROS). | ||||||||||||||||||||
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Tempol-d17,15N | 98.44% | Tempol-d17,15N is the deuterium labeled Tempol. Tempol is a general superoxide dismutase (SOD)-mimetic agent that efficiently neutralizes reactive oxygen species (ROS). | ||||||||||||||||||||
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Tempol | 99.73% | Tempol is a general superoxide dismutase (SOD)-mimetic agent that efficiently neutralizes reactive oxygen species (ROS). | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.90
HY-W0020044-Amino-TEMPO -
Similarity Score 0.83
HY-W001187RTempo (Standard) -
Similarity Score 0.82
HY-W7770724-Isocyanato-TEMPO,Technical grade -
Similarity Score 0.82
HY-129242Tempone -
Similarity Score 0.82
HY-151847N3-TEMPO -
Similarity Score 0.79
HY-23033Tempone-H -
Similarity Score 0.75
HY-Y17542,2,6,6-Tetramethylpiperidine-N-oxyl-4-amino-4-carboxylic acid -
Similarity Score 0.75
HY-B1382APempidine hydrochloride -
Similarity Score 0.74
HY-B1382Pempidine -
Explore the MedChemAI to find more analogs
References
- [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
- [2]. Vilar-Pereira G, et al. Resveratrol Reverses Functional Chagas Heart Disease in Mice. PLoS Pathog. 2016 Oct 27;12(10):e1005947. [Content Brief]
- [3]. Chatterjee PK, et al. Tempol, a membrane-permeable radical scavenger, reduces oxidant stress-mediated renal dysfunction and injury in the rat. Kidney Int. 2000 Aug58(2):658-73. [Content Brief]
