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Results for "

TIMD4

" in MedChemExpress (MCE) Product Catalog:

1

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4

Recombinant Proteins

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Cat. No. Compare Product Name Species Source
  • HY-P70976
    TIM-4/TIMD-4 Protein, Human (HEK293, His)

    T-cell immunoglobulin and mucin domain-containing protein 4; TIMD-4; T-cell immunoglobulin mucin receptor 4; TIM-4; T-cell membrane protein 4; TIMD4; TIM4

    		 Human HEK293
    T-cell immunoglobulin and mucin domain-containing protein 4 (TIMD4, TIM4) is a membrane protein in TIM family and is a phosphatidylserine receptor that plays different role in immune response including phagocytosis of apoptotic cells and T-cell regulation. TIMD4 controls T-cell activation in a bimodal fashion and promots the engulfment against apoptotic cells or exogenous particles. TIM-4/TIMD-4 Protein, Human (HEK293, His) is the recombinant human-derived TIM-4/TIMD-4 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of TIM-4/TIMD-4 Protein, Human (HEK293, His) is 291 a.a., with molecular weight of 60-90 kDa.
  • HY-P75552
    TIM-4/TIMD-4 Protein, Human (Biotinylated, HEK293, His)

    T-cell immunoglobulin and mucin domain-containing protein 4; TIMD4; TIM4

    		 Human HEK293
    TIM-4/TIMD-4 protein is a multifunctional phosphatidylserine receptor involved in multiple immune response functions. It participates in phagocytosis of apoptotic cells and exerts a bimodal regulatory effect on T cell activation—inhibiting initial T cell activation while promoting the proliferation of activated T cells through AKT1 and ERK1/2 phosphorylation. TIM-4/TIMD-4 Protein, Human (Biotinylated, HEK293, His) is the recombinant human-derived TIM-4/TIMD-4 protein, expressed by HEK293 , with C-His labeled tag. The total length of TIM-4/TIMD-4 Protein, Human (Biotinylated, HEK293, His) is 315 a.a., with molecular weight of ~32.7 kDa.
  • HY-P77236
    TIM-4/TIMD-4 Protein, Mouse (HEK293, His)

    T-cell immunoglobulin and mucin domain-containing protein 4; TIMD4; TIM4

    		 Mouse HEK293
    The TIM-4/TIMD-4 protein is a phosphatidylserine receptor that regulates immune responses through multiple actions. It participates in phagocytosis of apoptotic cells and regulates T cell function. TIM-4/TIMD-4 Protein, Mouse (HEK293, His) is the recombinant mouse-derived TIM-4/TIMD-4 protein, expressed by HEK293 , with C-His labeled tag.
  • HY-P700896
    TIM-4 Protein, Cynomolgus (HEK293, His)

    TIMD-4; TIMD4; TIM-4

    		 Cynomolgus HEK293
    TIM-4/TIMD-4 Protein, a phosphatidylserine receptor, regulates the immune response through diverse roles. It participates in apoptotic cell phagocytosis and modulates T-cell function. In T-cell activation, it induces cell cycle arrest in naive T-cells while enhancing activated T-cell proliferation through AKT1 and ERK1/2 phosphorylation. TIM-4/TIMD-4 plays a pivotal role in efferocytosis, directly binding to apoptotic cell phosphatidylserine for engulfment. Additionally, it promotes autophagy by suppressing NLRP3 inflammasome activity via the STK11/PRKAA1 pathway in a phosphatidylserine-dependent mechanism. TIM-4 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived TIM-4 protein, expressed by HEK293 , with C-His labeled tag. The total length of TIM-4 Protein, Cynomolgus (HEK293, His) is 281 a.a., with molecular weight of 70-80 kDa.

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