2 Results for "

Voacangine

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "Voacangine" in MCE Product Catalog:

Voacangine
Voacangine
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Cat. No.: HY-N7536
CAS No.: 510-22-5
Category:  

Alkaloids other families Other Diseases Plants Disease Research Fields Indole Alkaloids

Target:  

TRP Channel

Voacangine is an antagonist for TRPV1 and TRPM8 but as an agonist for TRPA1 (EC50=8 μM). Voacangine competitively blockes capsaicin binding to TRPV1 (IC50=50 μM). Voacangine competitively inhibits the binding of menthol to TRPM8 (IC50=9 μM) and it shows noncompetitive inhibition against icilin (IC50=7 μM). Voacangine selectively abrogates chemical agonist-induced TRPM8 activation and did not affect cold-induced activation. Voacangine is an alkaloid isolated from the root bark of Voacanga africana .
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Voacamidine
Voacamidine
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Cat. No.: HY-N18090
CAS No.: 6897-04-7
Category:  

Apocynaceae Alkaloids Voacanga africana Stapf Other Alkaloids Plants

Target:  

Drug Derivative

Voacamidine is an iboga-vobasinyl dimeric monoterpenoid indole alkaloid found in the root bark of Voacanga africana. Voacamidine undergoes cleavage in acid media to produce Voacangine (HY-N7536) .
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